首页|部分医疗机构《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》的实施情况调查

部分医疗机构《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》的实施情况调查

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目的 调查部分医疗机构《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》的实施情况.方法 通过问卷星调查56家医疗机构头孢菌素类药物皮肤试验(皮试)的管理情况及医务人员对《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》的掌握程度.结果 回收有效问卷407份(问卷有效率100%).《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》颁布后取消头孢菌素类药物常规皮试的医疗机构占比从17.86%提高到58.93%,仍然有32.14%的医疗机构未取消头孢菌素类药物常规皮试.医务人员对患者过敏史的甄别水平较高(占97.79%)、阳性皮试记录结果正确率较高(占96.07%)、大多数医疗机构(占96.43%)开展了严重过敏反应的抢救培训;但对头孢菌素类药物皮试适应证、皮试的意义、阳性/阴性预测值的意义、过敏性休克的抢救用药等掌握程度较低.结论 《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》实施情况不理想,医务人员对《β内酰胺类抗菌药物皮肤试验指导原则(2021年版)》的掌握程度有待提高.
Investigation and analysis of the current implementation of the"guidelines for skin testing of β-lactam antibacterial drugs(2021 edition)"by some medical institutions
AIM To investigate the implementation status of the"guidelines for skin testing of β-lactam antibacterial drugs(2021 edition)"in some medical institutions.METHODS A questionnaire via Questionnaire Star was used to assess the management of cephalosporin skin tests and the level of understanding among medical personnel of the"guidelines for skin testing of β-lactam antibacterial drugs(2021 Edition)"in 56 medical institutions.RESULTS A total of 407 valid questionnaires were collected achieving a response rate of 100%.Following the issuance of the guidelines,the proportion of medical institutions that ceased performing cephalosporin skin tests increased from 17.86%to 58.93%,while 32.14%of medical institutions had not discontinued skin tests for cephalosporin drugs.Medical personnel had a high level of discernment regarding allergic history(97.79%),and a high accuracy rate in recording positive skin test results(96.07%).Furthermore,the majority of medical institutions(96.43%)provided training for the management of severe allergic reactions.However,there was a relatively low understanding of indications for cephalosporin skin tests,the significance of skin tests,the implications of positive/negative predictive values,and the medication for rescuing anaphylactic shock.CONCLUSION The implementation status of the guidelines is suboptimal.There is a need to improve the level of understanding of the guidelines among medical personnel.

β-lactamscephalosporinsantimicrobial drugskin test

何苗、张海霞、赵昕、王晓玲

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湖南省儿童医院药学部,长沙 410007

首都医科大学附属北京儿童医院药学部,北京 100045

β内酰胺类药物 头孢菌素类药物 抗菌药物 皮肤试验

2024

中国临床药学杂志
中国药学会

中国临床药学杂志

CSTPCD
影响因子:0.502
ISSN:1007-4406
年,卷(期):2024.33(1)
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