Investigation and analysis of off-label drug use of Chinese patent medicine in medical institutions of different levels
AIM To investigate the current situation of off-label use of Chinese patent medicines(CPMs)in various medical institutions at all levels and analyze the causes,so as to promote the rational application of CPMs in clinical practice.METHODS A questionnaire on the off-label use of CPMs was designed using Questionnaire Star.A total of 42 valid questionnaires were obtained from 44 medical institutions of different levels and types.The off-label use of CPMs was analyzed from the following aspects:the phenomenon of off-label use of CPMs,management system,approval process,manifestation form of reflection after approval and filing,implementation of the system,follow-up analysis and prescription review.RESULTS The off-label use of CPMs was more common in high-grade and specialized medical institutions.The phenomenon of off-label use of CPMs in the medical institutions of traditional Chinese medicine series was more than that in the medical institutions of Western series and integrated Chinese and Western series.The medical institutions with high levels were better than the medical institutions with low levels in terms of management systems and approval processes.The medical institutions of the Western medicine series were superior to the medical institutions of the Chinese medicine series in terms of system implementation,prescription authorization,filing data review and tracking and analysis.CONCLUSION Improving the management system of off-label use of CPMs,strengthening authorization management of Chinese patent medicine prescriptions and tracking the clinical outcomes and adverse reactions of off-label use of CPMs are conducive to improving the current situation of off-label use of CPMs and improving the rational clinical application of CPMs.
Chinese patent medicineoff-label drug usemanagement systemapproval processinformed consentprescription auditprescription evaluation
国家科技期刊平台
NSTL
万方数据
