Efficacy,safety and economic evaluation of prophylactic antibiotics in patients with radiofrequency therapy of trigeminal neuralgia
AIM To evaluate the efficacy,safety and economy of prophylactic use of antibiotics in trigeminal nerve radiofrequency ablation,and to provide reference for clinical rational drug use.METHODS A total of 51 patients who underwent radiofrequency ablation of the trigeminal nerve in the department of pain medicine from January to December 2022 were retrospectively collected.Among them,31 patients were treated with prophylactic antibiotics as the observation group,and 20 patients were treated without prophylactic antibiotics as the control group.The hospitalization time,effective rate,incidence of adverse events and incidence of infection were compared between the 2 groups.The decision tree model was established for economic evaluation.RESULTS There was no significant difference in the length of hospital stay,effective rate and incidence of adverse events between 2 groups(P＞0.05).There was no postoperative infection in 2 groups.According to the cost-effectiveness analysis,the non-prophylactic antibiotic therapy was an economically superior option.CONCLUSION Radiofrequency ablation of trigeminal neuralgia without prophylactic use of antibiotics has shown no significant effect on clinical results and could save medical costs.
国家科技期刊平台
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