A study on clinical medication characteristics of Tanreqing injection based on real-world
AIM To analyze potential issues in the clinical application of Tanreqing injection and propose corresponding solutions,by analyzing the characteristics of Tanreqing injection in the real world.METHODS Hospitalized patients treated with Tanreqing injection in 10 tertiary medical institutions from January 2015 to December 2023 were collected.The information of age,gender,hospitalization department,hospitalization time,disease diagnosis,laboratory examination,medication status and other information were extracted,and clinical medication characteristics of Tanreqing injection were analyzed.RESULTS A total of 18 854 patients were included,with a male-to-female ratio of 1.12∶1.The average age was 62(49,72)years,and the length of hospital stay was 9(6,13)days.In diagnostic information,lung-related diseases accounted for the highest proportion(59.02％).Regarding laboratory tests,levels of C-reactive protein and the percentage of neutrophils were above normal reference ranges.The single dose of the medication was(27.69±7.11)mL,and 99.75％of the medical instructions prescribed a frequency of once daily(qd).The duration of medication use was 5(2,9)days,with the cumulative dose amounting to 120(60,240)mL.Administration was exclusively by intravenous drip,and 0.9％sodium chloride injection solution served as the solvent in 60.3％of the cases.Among the combined medications,antibacterial drugs accounted for the highest proportion(53.55％).Within the single antibacterial drug combinations,β-lactam drugs made up the highest proportion at 42.5％.The combination of β-lactam drugs and quinolones was the most common among the combinations of 2 antibacterial drugs,with a confidence level of 63.27％.Within 14 days of medication,the disease remission rate showed an upward trend.CONCLUSION Tanreqing injection is mainly used for the treatment of respiratory diseases complicated with infection.The usage and dosage are consistent with the instructions.It is frequently combined with antibacterial drugs in clinical practice.Most patients benefit significantly within 14 days of medication.
万方数据
维普
