Comparison of curative effect of drospirenone and ethinyl estradiol combined with Kuntai capsule in the treatment of polycystic ovary syndrome
AIM To compare the curative effect of drospirenone and ethinyl estradiol combined with Kuntai capsule on patients with polycystic ovary syndrome.METHODS A total of 86 patients with polycystic ovary syndrome were as the study subjects and randomly separated into reference group and research group,with 43 patients in each group.Patients in the reference group were treated with drospirenone and ethinyl estradiol,and patients in the research group were treated with drospirenone and ethinyl estradiol combined with Kuntai capsules.The efficacy,traditional Chinese medicine(TCM)syndrome score,ovulation,pregnancy and sex hormone levels of 2 groups were compared.RESULTS The total effective rate of research group was 90.70％,which was higher than 69.77％of reference group,with a significant difference(P＜0.05).After treatment,the TCM syndrome scores of early menstruation,low volume,red color,five upset heat,dry throat,thirst,dizziness,palpitation,lumbago and leg weakness in the study group were lower than those in the control group(P＜0.05).The ovulation rate and pregnancy rate of research group were higher than those of reference group(P＜0.05).After treatment,the levels of serum estradiol(E2)and follicle stimulating hormone(FSH)in research group were higher than those in reference group(P＜0.05),and the levels of luteinizing hormone(LH)and testosterone(T)were lower than those in reference group(P＜0.05).CONCLUSION Drospirenone and ethinyl estradiol combined with Kuntai capsules can improve the therapeutic effect,promote the ovulation rate and pregnancy rate in patients with polycystic ovary syndrome,which is worthy of clinical application.
drospirenone and ethinyl estradiolKuntai capsulepolycystic ovary syndromeefficacy
万方数据
维普
