首页|基于熵权结合TOPSIS法评价康莱特注射液临床使用合理性

基于熵权结合TOPSIS法评价康莱特注射液临床使用合理性

扫码查看
目的 建立熵权结合TOPSIS法,评价康莱特注射液临床使用的合理性.方法 参考康莱特注射液的药品说明书,结合专家共识,制定康莱特注射液评价标准.随机抽取2021年10月至2023年10月在我院使用康莱特注射液的病历126份,根据制定的评价标准,利用熵权结合TOPSIS法评价康莱特注射液临床使用合理性.结果 在评价的126份病历中,相对接近度为1的病历有1份,占比0.79%;相对接近度<1且≥0.6的病历有61份,占比48.41%;相对接近度<0.6的病历有64份,占比50.79%.造成用药不合理的主要原因为超药品说明书用药,主要表现为超适应证用药.结论 康莱特注射液的临床应用存在超适应证问题较多,临床需加强监管,进一步规范其合理使用.
Evaluation of the clinical rationality of Kanglaite injection based on entropy weight combined with TOPSIS method
AIM The entropy weight combined with TOPSIS method was established to evaluate the rationality of clinical use of Kanglaite injection.METHODS According to the manual of Kanglaite injection and the expert consensus,the evaluation criteria of Kanglaite injection was formulated.A total of 126 medical records of patients using Kanglaite injection in our hospital from October 2021 to October 2023 were randomly selected.The rationality of clinical use of Kanglaite injection was evaluated by TOPSIS method based on entropy weight according to the established evaluation criteria.RESULTS The results showed that there was a case with a relative proximity degree of 1,accounting for 0.79%.Additionally,there were 61 cases with a relative proximity degree<1 and ≥ 0.6,accounting for 48.41%.The remaining 64 cases were found to have a relative proximity degree of less than 0.6.The proportion was 50.79%.The main problem of the unreasonable use was off-label drug use,which was mainly manifested as extra-indication drug use.CONCLUSION There are many extra-indication drug use problems in the clinical application of Kanglaite injection,and clinical supervision should be strengthened to promote its rational use.

Kanglaite injectionentropy weight combined with TOPSIS methodrationality of drug use

耿亚迪、宁丽娟、李正、沈爱宗

展开 >

中国科学技术大学附属第一医院-安徽省立医院药学部,合肥 230001

康莱特注射液 熵权结合TOPSIS法 用药合理性

2024

中国临床药学杂志
中国药学会

中国临床药学杂志

CSTPCD
影响因子:0.502
ISSN:1007-4406
年,卷(期):2024.33(8)
  • 19