胃肠道移植物抗宿主病营养支持的研究进展
Research progress on nutritional support for gastrointestinal graft-versus-host disease
于海燕 1张雪亭 1刘岩 1路筝 2孙笑天3
作者信息
- 1. 解放军总医院第五医学中心消化内科消化内镜中心,北京 100071
- 2. 解放军总医院第五医学中心肝病学部消化内镜中心,北京 100039
- 3. 解放军总医院京南医疗区综合内科,北京 100071
- 折叠
摘要
胃肠道移植物抗宿主病是造血干细胞移植术后最严重的并发症之一,可发生于各年龄段患者,临床表现有恶心、呕吐、腹痛、腹泻等,严重者可直接影响患者的临床预后和疗效.该文就胃肠道移植物抗宿主病营养支持及饮食管理策略的研究进展做一综述,主要从营养风险筛查及评估、营养支持方案制定、营养监测、营养教育、营养干预途径及时机等方面进行分析研究,形成阶梯化营养支持模式,减少胃肠道移植物抗宿主病患者营养不良的风险,对改善患者全身状况、缓解消化道症状和降低并发症发生风险等都具有十分重要的临床意义.
Abstract
Gastrointestinal graft versus host disease is one of the most severe complications after hematopoietic stem cell transplantation,which can occur in patients of any age groups.Its clinical manifestations include nausea,vomit,abdominal pain,diarrhea and the like.Severe gastrointestinal graft versus host disease could directly influence the patients'clinical prognosis and therapeutic efficacy of transplantation.Here we had a review of the research progress on nutritional support and diet management strategies for gastrointestinal graft versus host disease.It is of great clinical significance to form a step-wise nutritional support model to reduce the risk of malnutrition in patients with gastrointestinal graft versus host disease,which would contribute to improving patients'general condition,relieving digestive tract symptoms,and reducing the risk of complications.
关键词
胃肠道/移植物抗宿主反应/营养支持Key words
Gastrointestinal/Graft-versus-host disease/Nutritional support引用本文复制引用
出版年
2024
NETL
NSTL
万方数据