Analysis of clinical characteristics in 18 adults with severe varicella
Objective:To analyze the clinical characteristics of adult patients with severe varicella,and enhance the understanding of this disease.Methods:The clinical data of 18 patients with severe varicella ad-mitted to our hospital from January 2018 to March 2024 were retrospectively analyzed.Results:Of the 18 pa-tients,12 were males and 6 were females.The average age was 32.1 years(ranging from 18 to 50).Nine pa-tients(50.0%)received long-term immunosuppressive drugs due to organ transplantation,rheumatoid arthri-tis,or other underlying diseases.Multiple laboratory abnormalities included decreased platelet count(12 ca-ses,66.7%),elevated liver enzyme(15 cases,83.3%),elevated myocardial enzyme(18 cases,100%),elevated NT-pro BNP(15 cases,83.3%),elevated D-dimer(16 cases,88.9%),and elevated procalcitonin(14 cases,77.8%).Six patients(33.3%)discontinued treatment due to poor outcomes,of them,3 cases died.There were 15 patients infected with pneumonia,and 11 patients had type Ⅰ respiratory failure.Con-clusions:Severe varicella is more prevalent in adult males,and has a relatively high mortality rate.Immuno-compromised adults are at higher risk for severe varicella infection.TypeⅠrespiratory failure is frequently ob-served in adults with severe varicella complicated with pulmonary infection.
severe varicellaadultvaricella-zoster viruspneumonia
万方数据
维普
