Cladophialophora carrionii infection:two cases report and literature review
Both patients were elderly farmers with a history of trauma.The skin lesions presented as a-symptomatic proliferative plaques.Histopathological examination showed typical sclerotic bodies.Fungal cul-ture identified the fungal as Cladophialophora carrionii.The patient were treated with oral itraconazole 200 mg twice daily,topical fusidic acid cream and sertaconazole nitrate cream.One month later,the patient's skin le-sions improved.We summarized the characters of cases reported in literature,which included Cladophialopho-ra carrionii infection in China were mainly middle-aged and elderly people(mean age 53.7 years),and 50%of the patients had a history of trauma.Upper limbs were the most commonly affected sites,and plaques were the most common manifestation.The average course of disease was about 5.4 years,and due to the lack of sub-jective symptoms,patients often delay seeking medical advice,which may lead to the spread of infection and disability.Cladophialophora carrionii was sensitive to antifungal drugs.
万方数据
维普
