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左足颗粒细胞瘤一例

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颗粒细胞瘤(granular cell tumor,GCT)是一种罕见软组织肿瘤,临床皮损不典型,好发于头颈部,发生于足部者少见.本患者左足跟角质性斑块 20 年,组织病理示:真皮内见大圆形细胞排列成巢状,细胞核小、居中,胞质内见嗜酸性颗粒.免疫组化:S-100(+)、SOX10(+)、NSE(+)、CD68(+).诊断为颗粒细胞瘤,予以手术切除.
Granulosa cell tumor on the left heel:a case report
Granular cell tumor(GCT)is a rare soft tissue tumor.The skin lesions are atypical and usually occur in the head and neck,but rarely on the feet.The patient presented with keratinous plaques on the left heel for 20 years.Histopathology showed large circular cells arranged in nests within the dermis,the nucleus is small and centered,acidophilic granules can be seen in the cytoplasm.Immunohistochemistry showed S-100(+),SOX10(+),NSE(+),CD68(+).The patient was diagnosed with granulosa cell tumor and underwent surgical resection.

left heelgranulosa cell tumordiagnosis

张雪燕、张铭凯、曹楠、陈声利

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山东第一医科大学附属皮肤病医院,山东 济南,250022

山东省皮肤病性病防治研究所,山东 济南,250022

左足跟 颗粒细胞瘤 诊断

2025

中国麻风皮肤病杂志
中国麻风防治协会,山东省皮肤病性病防治研究所

中国麻风皮肤病杂志

影响因子:0.302
ISSN:1009-1157
年,卷(期):2025.41(1)