In order to construct multi-order and multi-factor analytical model influencing spatial disorientation in general aviation flights,5 first-order factors and 22 second-order factors affecting spa-tial disorientation are identified including flight situation,aircraft fault,pilot physical and mental health,crew cooperation and pilot expertise based on the subjective report analysis of the pilots in spatial diso-rientation accidents and from three perspectives of man-aircraft-environment.The importance of 22 sec-ond-order factors is rated by 75 general aviation pilots and the data is analyzed by analytic hierarchy process(AHP).The results reveal that the physical and mental health of the pilots is the top first-order factor that triggers spatial disorientation.The top five second-order factors are situation awareness and decision making,fatigue,flight disciplines,physical health status and automated system operation.The results provide a reference for general aviation to achieve a multi-method approach to avoiding spatial disorientation and training general aviation pilots to overcome spatial disorientation.