Correlation between hand grip strength value and all-cause death in Beijing rural elderly
Objective To explore the correlation between hand grip strength(HGS)and all-cause death in the rural elderly of Beijing,and provide the scientific basis for understanding the correlation between HGS and all-cause death in rural elderly.Methods Data were from the Beijing Elderly Comprehensive Health Cohort Study(BECHCS).From June to September 2014,two-stage random sampling method was used to select the elderly residents(≥60 years old)in Jugezhuang town and Fengjiayu town of Miyun district as the subjects.The investigation was conducted with questionnaires,physical examinations and laboratory test,and one time of following up every 2-3 years until March 31,2021.The t test,x2tests and Fisher's precision probability test were used to analyze the data.The used software was SPSS 26.0 and R 4.2.3.The Kaplan-Meier method was used to depict the cumulative survival curves in the rural elderly with different grip strengths.The Cox proportional hazards regression models were used to analyze the correlation between HGS and all-cause death in the rural elderly,the subgroup analysis performed according to gender and age.Results The included subjects were 2 004 cases,the age median was 68.00 years old(P25-P75:64.00-74.00 years old).The HGS median was 22.08 kg(P25-P75:16.00-29.95 kg),915 cases(45.7％)had low HGS and 1 089 cases(54.3％)had normal HGS.As of March 31,2021,the median of follow-up duration of the study was 80.36 months(P25-P75:68.93-81.06 months).The mortality was 11.5％(231 cases/2 004 cases),and the accumulative total death density was 15.7/104 person-months.Multivariate Cox proportional risk regression model showed that as compared with the low HGS group,the risk of all-cause death in normal HGS group decreased by 36.7％(HR=0.633,95％CI:0.475-0.846,P＜0.01),and when the HGS value increased 5 kg,the risk of all-cause death in rural elderly decreased by 12.8％(HR=0.872,95％CI:0.808-0.940,P＜0.01).The results stratified by sex showed that in rural male elderly,as compared with the low HGS value group,the risk of all-cause death in normal HGS group reduced by 43.3％(HR=0.567,95％CI:0.386-0.833,P＜0.05);when HGS value increased 5 kg,the risk of all-cause death decreased by 11.7％(HR=0.883,95％CI:0.808-0.964,P＜0.01);in rural female elderly,when HGS value increased 5 kg,the risk of all-cause death decreased by 15.9％(HR=0.841,95％CI:0.717-0.985,P＜0.01).The results stratified by age showed that in 60-69 years old group,as compared with the low HGS value group,the risk of all-cause death in normal HGS group reduced by 45.7％(HR=0.543,95％CI:0.319-0.924,P＜0.05),and when the HGS value increased 5 kg,the risk of all-cause death decreased by 15.2％(HR=0.848,95％CI:0.734-0.981,P＜0.01);in 70-79 years old group,as compared with the low HGS value group,the risk of all-cause death in normal HGS group reduced by 49.4％(HR=0.506,95％CI:0.332-0.770,P＜0.05),and when the HGS value increased 5 kg,the risk of all-cause death decreased by 16.4％(HR=0.836,95％CI:0.749-0.933,P＜0.05);in ≥80 years old group,there was no significant difference between HGS value and risk of all-cause death(P＞0.05).Conclusion The HGS is closely related to the risk of all-cause death in the elderly population in rural areas of Beijing.It should pay attention to rural elderly with 70-79 years old and females;according to rural life characteristics,the corresponding training strategy is formulated.
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