首页|24 h尿钠、24 h尿钾以及钠钾比与肥胖、中心性肥胖的关联分析

24 h尿钠、24 h尿钾以及钠钾比与肥胖、中心性肥胖的关联分析

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目的 了解我国成年人群24 h尿钠、24 h尿钾以及钠钾比与肥胖、中心性肥胖的关联性,为肥胖预防策略的制订提供科学依据.方法 研究数据来源于2018年10-12月开展的中英减盐行动"以社区为基础的中国居民减盐综合干预整群随机对照研究"基线调查数据.采用多阶段随机抽样的方法选取河北、黑龙江、江西、湖南、四川和青海6省18~75岁居民2 639名为研究对象,进行体格检查,采集24 h尿液检测24 h尿钠、24 h尿钾和尿钠钾比水平.采用SAS 9.4软件进行t检验、x2检验、多重线性回归分析和多因素logistic回归分析.结果 纳入分析2 639名研究对象的平均年龄为(47.4±12.8)岁,肥胖率为17.39%,中心性肥胖率为63.55%.24 h尿钠水平为(192.93±79.19)mmol/d,24 h尿钾水平为(40.15±15.56)mmol/d,尿钠钾比水平为(5.18±2.18).校正相关混杂因素后,多因素logistic回归模型结果显示,与24 h尿钠最低水平组相比,最高水平组与肥胖、中心性肥胖患病高风险相关(OR=2.427,95%CI:1.739~3.387;OR=2.402,95%CI:1.826~3.158);与尿钠钾比最低水平组相比,最高水平组均与肥胖、中心性肥胖患病高风险相关(OR=1.414,95%CI:1.040~1.922;OR=1.477,95%CI:1.157~1.885),均有统计学意义(P<0.05);24h尿钾与肥胖、中心性肥胖的关联均无统计学意义(P>0.05).结论 24 h尿钠、钠钾比与肥胖、中心性肥胖存在关联,提示肥胖人群应减少钠盐摄入,同时控制钠钾摄人比例.
Correlation between 24 h urinary sodium,24 h urinary potassium,urinary sodium-potassium ratio and obesity/central obesity
Objective To analyze the association of 24 h urinary sodium,24 h urinary potassium and sodium-potassium ratio with obesity/central obesity in adults of China,and provide the scientific basis for the formulation of obesity prevention strategies.Methods The data were from the baseline investigation data of"a community-based cluster randomized controlled study of comprehensive intervention on salt reduction among Chinese residents"of China-UK salt reduction action developed from October to December 2018.Method of multi-stage random sampling was used to select 2 639 residents(18-75 years old)from six provinces(Hebei,Heilongjiang,Jiangxi,Hunan,Sichuan and Qinghai)as the subjects.The investigation was performed with physical examination,collecting 24 h urinary sodium,24 h potassium,sodium-potassium ratio.The t test,x2 test,multiple linear regression analysis and multivariate logistic regression were used to analyze the data.The used software was SAS 9.4.Results In 2 639 subjects,the average age was(47.4±12.8)years old,obesity rate was 17.39%and central obesity rate was 63.55%.The 24 h urinary sodium,24 h potassium,sodium-potassium ratio were(192.93±79.19)mmol/d,(40.15±15.56)mmol/d and 5.18±2.18,respectively.After adjusting the related confounding factors,the multivariate logistic regression showed that as compared with the lowest 24 h urinary sodium group(Q1),the highest 24 h urinary sodium group(Q4)was related to high risk of obesity and central obesity(OR=2.427,95%CI:1.739-3.387;OR=2.402,95%CI:1.826-3.158,respectively);as compared with the lowest 24 h urinary sodium-potassium ratio group,the highest 24 h urinary sodium-potassium ratio group was related to high risk of obesity and central obesity(OR=1.414,95%CI:1.040-1.992;OR=1.477,95%CI:1.157-1.885,respectively),P<0.05.The 24 h urinary potassium was not related to the obesity and central obesity(P>0.05).Conclusion The 24 h urinary sodium and sodium-potassium ratio are related to obesity and central obesity.It indicates that intake of sodium should be reduced,and the sodium-potassium intake ratio should be controlled.

SodiumPotassiumObesity24 h urine

潘宁宁、李晴、刘敏、李园、张普洪、白雅敏、徐建伟

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中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京 100050

北京大学医学部乔治健康研究所,北京 100088

肥胖 24h尿

英国国立健康研究院资助中英减盐项目

16/136/77

2024

中国慢性病预防与控制
中华预防医学会,天津市疾病预防控制中心

中国慢性病预防与控制

CSTPCD北大核心
影响因子:1.093
ISSN:1004-6194
年,卷(期):2024.32(1)
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