Correlation between cardiovascular health level and risk of all-cause death or death from cardiovascular disease
Objective To explore the correlation between cardiovascular health(CVH)level and risk of all-cause death or death from cardiovascular disease(CVD)in Chinese residents,and provide the reference for the prevention and control of CVD.Methods The study included 64 987 subjects from the 2015 China Chronic Disease and Risk Factors Surveillance(CCDRFS)who participated in the dietary survey.The 2015 CCDRFS used a multi-stage stratified cluster random sampling method to select the residents from 298 monitoring sites in 31 provinces(autonomous regions and municipalities directly under the Central Government).According to evaluation standards of Life's Essential 8(LE8),CVH score,health behavior score and health factor score were calculated.Software SAS 9.4 and software R 4.3.1.were used for data cleaning and statistical analysis.The weighted Cox proportional risk regression model was used to analyze the association of CVH level with the risk of all-cause death and death from cardiovascular disease.Association of CVH scores with risk of all-cause and CVD mortality was estimated using a restrictive cubic spline model.Results The study included 64 987 subjects.The subjects with higher,moderate and lower baseline CVH leves were 17 980(27.7%),44 368(68.3%)and 2 639(4.0%),respectively.The weighted Cox proportional risk regression models showed that as compared to the subjects with low CVH level,the risk of all-cause death and CVD death in the subjects with high CVH level was lower(HR=0.30,95%CI:0.21-0.42;HR=0.19,95%CI:0.10-0.36).For every 10-point increase in CVH score,the risk of all-cause and CVD mortality decreased by 24%(HR=0.76,95%CI:0.70-0.82)and 33%(HR=0.67,95%CI:0.58-0.77),respectively.The risk of all-cause mortality and CVD mortality in subjects decreased with increasing CVH score(Pnon-linear>0.05).Conclusion Promoting a healthy lifestyle,improving the management and control of chronic disease risk factors,and obtaining a high level of CVH can significantly reduce the risk of mortality from all-cause and CVD among adults in China.
Cardiovascular healthLife's Essential 8All-cause of deathDeath from cardiovascular disease