Association of obesity status with force volume in 1 second reduction in community middle-aged and elderly adults(≥40 years old)
Objective To understand the association of obesity status with force volume in 1 second(FEV1)reduction in community middle-aged and elderly adults(≥40 years old),and provide the reference for the prevention and treatment of chronic respiratory diseases in middle-aged and elderly adults in the communities.Methods Based on the 2016 Shanghai suburban natural population cohort,the random sampling method was used to select 3 149 cohort members(≥40 years old)in 2021 as the subjects.The investigation was performed with pulmonary function examinations and questionnaires.The subjects were divided into different obesity types based on BMI and waist circumference measurements.The t test,Mann Witney U test,x2test and multifactorial unconditional logistic regression were used to analyze the data.The used software was SPSS 22.0.Results The rate of FEV1 reduction(FEV1%Pred<80%)in the 3 149 subjects was 14.8%,the FEV1 reduction rate(21.1%)in males was significantly higher than that(10.7%)in females(P<0.01).The BMI overweight and obesity rates of the subjects were 43.7%and 17.9%,respectively;and the central obesity rate was 30.9%.The results of multifactorial logistic regression analysis showed that central obesity was associated with a higher risk of FEV1 reduction(OR=1.70),and overweight(OR=0.63)or obesity(OR=0.64)of BMI was associated with lower risk of FEV1 reduction(P<0.01).In the different obesity types,the risk of lower FEV1 in those with overweight/obese BMI+normal waist circumference was lower than that in those with lean/normal BMI+normal waist circumference(OR=0.66),and the same association existed in the male population after subgender analysis(OR=0.63);the risk of lower FEV,in those with lean/normal BMI+central obesity was higher than that in the group with lean/normal BMI+normal waist circumference(OR=1.93),the same result also existed in females(OR=2.25),P<0.05.Conclusion The rate of FEV1 reduction in residents with central obesity is higher than that in those with normal waist circumference;the FEV1 reduction rate in residents with low BMI is much higher.Therefore,middle-aged and elderly residents in the community should adjust their lifestyles to maintain appropriate body weight and reduce waist circumference in order to prevent lung function reduction.
ObesityForce volumn in 1 second reductionPulmonary function testsChronic obstructive pulmonary diseaseBronchial asthma