首页|社区40岁及以上中老年人肥胖状态与第1秒用力呼气容积下降的关联研究

社区40岁及以上中老年人肥胖状态与第1秒用力呼气容积下降的关联研究

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目的 了解社区40岁及以上中老年人肥胖状态与第1秒用力呼气容积(FEV1)下降的关联,为社区中老年人慢性呼吸系统疾病防治提供参考.方法 基于2016年上海市郊区自然人群队列,于2021年采用随机抽样法抽取共3 149名40岁及以上队列成员开展肺功能检查及问卷调查,根据体质指数(BMI)和腰围测量结果分为不同的肥胖类型.采用SPSS 22.0进行t检验、Mann-Whitney U检验、x2检验和多因素非条件logistic回归分析.结果 3 149名研究对象的FEV1下降(FEV1%Pred<80%)率为14.8%,男性(21.1%)高于女性(10.7%),差异有统计学意义(P<0.01).研究对象的BMI超重率和肥胖率分别为43.7%和17.9%,中心性肥胖率为30.9%.多因素logistic回归分析结果显示,中心性肥胖与FEV1下降高风险相关(OR=1.70),BMI超重(OR=0.63)或肥胖(OR=0.64)与FEV1下降低风险相关,均有统计学意义(P<0.01).在不同的肥胖类型中,BMI超重/肥胖+腰围正常者FEV1下降的风险低于BMI偏瘦/正常+腰围正常者(OR=0.66),分性别分析后,男性居民中同样存在该关联(OR=0.63);BMI偏瘦/正常+中心性肥胖者的FEV1下降风险高于BMI偏瘦/正常+腰围正常组(OR=1.93),该结果在女性中同样成立(OR=2.25),均有统计学意义(P<0.05).结论 中心性肥胖者相较于腰围正常者FEV1下降率更高;而对于腰围正常者,BMI较低者FEV1下降率更高.因此社区中老年人应调整生活方式以维持适当体重和减少腰围,从而预防肺功能下降.
Association of obesity status with force volume in 1 second reduction in community middle-aged and elderly adults(≥40 years old)
Objective To understand the association of obesity status with force volume in 1 second(FEV1)reduction in community middle-aged and elderly adults(≥40 years old),and provide the reference for the prevention and treatment of chronic respiratory diseases in middle-aged and elderly adults in the communities.Methods Based on the 2016 Shanghai suburban natural population cohort,the random sampling method was used to select 3 149 cohort members(≥40 years old)in 2021 as the subjects.The investigation was performed with pulmonary function examinations and questionnaires.The subjects were divided into different obesity types based on BMI and waist circumference measurements.The t test,Mann Witney U test,x2test and multifactorial unconditional logistic regression were used to analyze the data.The used software was SPSS 22.0.Results The rate of FEV1 reduction(FEV1%Pred<80%)in the 3 149 subjects was 14.8%,the FEV1 reduction rate(21.1%)in males was significantly higher than that(10.7%)in females(P<0.01).The BMI overweight and obesity rates of the subjects were 43.7%and 17.9%,respectively;and the central obesity rate was 30.9%.The results of multifactorial logistic regression analysis showed that central obesity was associated with a higher risk of FEV1 reduction(OR=1.70),and overweight(OR=0.63)or obesity(OR=0.64)of BMI was associated with lower risk of FEV1 reduction(P<0.01).In the different obesity types,the risk of lower FEV1 in those with overweight/obese BMI+normal waist circumference was lower than that in those with lean/normal BMI+normal waist circumference(OR=0.66),and the same association existed in the male population after subgender analysis(OR=0.63);the risk of lower FEV,in those with lean/normal BMI+central obesity was higher than that in the group with lean/normal BMI+normal waist circumference(OR=1.93),the same result also existed in females(OR=2.25),P<0.05.Conclusion The rate of FEV1 reduction in residents with central obesity is higher than that in those with normal waist circumference;the FEV1 reduction rate in residents with low BMI is much higher.Therefore,middle-aged and elderly residents in the community should adjust their lifestyles to maintain appropriate body weight and reduce waist circumference in order to prevent lung function reduction.

ObesityForce volumn in 1 second reductionPulmonary function testsChronic obstructive pulmonary diseaseBronchial asthma

张艺璇、苏旭燕、侯珊珊、李静、尹欣、罗炜、俞敏君、臧金鑫、王伟、吴毅凌、赵琦、王琴、赵根明、姜永根、姜庆五、王娜

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复旦大学公共卫生学院复旦大学公共卫生安全教育部重点实验室,上海 200032

上海市松江区疾病预防控制中心慢性病防治科,上海 201600

上海市松江区中山街道社区卫生服务中心预防保健科

上海市松江区泖港镇社区卫生服务中心预防保健科

上海市松江区新桥镇社区卫生服务中心预防保健科

上海市松江区佘山镇社区卫生服务中心预防保健科

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肥胖 第1秒用力呼气容积下降 肺功能检查 慢性阻塞性肺疾病 支气管哮喘

国家自然科学基金国家重点研发计划精准医学重点专项

820736342017YFC0907000

2024

中国慢性病预防与控制
中华预防医学会,天津市疾病预防控制中心

中国慢性病预防与控制

CSTPCD北大核心
影响因子:1.093
ISSN:1004-6194
年,卷(期):2024.32(5)