Effects of meteorological factors and air pollutants on chronic obstructive pulmonary disease patient visits in Tianjin and their interactive effects
Objective To explore the effects of meteorological factors and air pollutants on chronic obstructive pulmonary disease(COPD)patient visits and their interactive effects,and provide the basis for health weather forecast and service and for prevention and treatment of COPD.Methods The data of COPD were from medical treatment data of a tertiary hospital of Tianjin from January 1,2012 to December 31,2021.Meteorological data of same duration were from Tianjin Meteorological Information Center,Tianjin City Climate Monitoring Station from 2012 to 2021.Air environment data were from Tianjin Ecological Environment Monitoring Center.Generalized additive model(GAM)was used to analyze the the effects and interaction of meteorological factors and air pollutants on COPD patient visits.The used software was R 4.1.2.Results GAM univariate analysis showed that when the average air temperature decreased by more than 5.0 ℃ within 24 h,for each 1 ℃ decrease,daily COPD patient visits increased by 3.98％after 1 d;when the daily temperature difference was greater than 13.2℃,for each 1 ℃ increase,COPD patient visits increased by 1.44％after 3 d;when PM10＞233 μg/m3 or PM2.5＞128 μg/m3 or O3＞175 μg/m3,for every 10 μg/m3 increase,daily COPD visits increased by 1.00％to 2.53％after 5 to 7 d.The analysis of interaction showed that in winter,the average temperature decreased by more than 5.0 ℃,and the PM10 concentration was≥227 μg/m3,for 10 μg/m3 increase,the daily visits of COPD increased by 27.39％(95％CI:0.50％-63.04％);or for each 10 μg/m3 increase in PM2.5 concentration,there was an 8.83％increase in daily COPD visits(95％CI:1.41％-20.24％).In spring and summer,the daily temperature difference was less than 9 ℃ and the O3 concentration was＞193 μg/m3,for every 10 μg/m3 increase in O3 concentration,the daily COPD patient visits increased by 4.69％(95％CI:1.71％-7.65％).Conclusion The average temperature drop within 24 h,the daily temperature difference,and the moderate environmental pollution affects COPD patient visits,and there is an interaction between meteorological factors and air pollutants.
Chronic obstructive pulmonary diseaseMeteorological factorAir pollutantGeneralized additive model
NETL
NSTL
万方数据
