Follow-up study of premature death and influencing factors in high-risk population with cardio-cerebrovascular diseases of Beijing
Objective To understand the premature death and influencing factors in high-risk population with cardio-cerebrovascular diseases of Beijing,and provide the basis for the prevention and treatment of cardiovascular and cerebrovascular diseases and the risk factor control in the middle-aged and elderly people.Methods The data were from"Beijing Community Stroke Screening and Prevention and Control Project",the project conducted a baseline survey from 2010 to 2012,the subjects from 16 districts(counties)in Beijing were screened,the investigation was performed with questionnaire and physical examination.Follow-up visits was conducted to December 31,2021.A total of 38 093 residents at high risk of cardiovascular and cerebrovascular diseases were selected.The x2 test and trend x2 test were used to analyze the data.Cox proportional hazards regression models was used to analyze influencing factors associated with premature death.Results The subjects were 38 093 cases(58-69 years old),the average follow-up duration was(9.52±1.41)years,the number of premature death was 1 158 cases,the premature mortality was 3.19/1 000 person years.The main causes of premature death were cancer(42.49％)and cardiovascular and cerebrovascular diseases(35.58％).The proportion of premature deaths caused by cancer in urban residents was higher(50.69％)than that(34.26％)in suburbs residents,the proportion(28.10％)of premature deaths caused by cardiovascular and cerebrovascular diseases in urban residents was significantly lower than that(43.08％)in suburbs residents(P＜0.01).The results of the Cox proportional hazards regression model analysis showed that male(HR=1.739,95％CI:1.498-2.019),lower age group(58-59 years old HR=3.558,95％CI:2.922-4.334;60-64 years old HR=2.263,95％CI:1.949-2.627),lower educational level(primary school and below HR=1.812,95％CI:1.437-2.285;junior high school or technical secondary school or senior high school HR=1.514,95％CI:1.165-1.968),living in the suburbs(HR=1.159,95％CI:1.022-1.314),having quit smoking(HR=1.358,95％CI:1.090-1.692),current smoking(HR=1.220,95％CI:1.038-1.433),unhealthy eating habits(HR=1.130,95％CI:1.006-1.270),elevated physical blood pressure(HR=1.302,95％CI:1.155-1.468)had a higher risk of premature death;early mortality risk was lower in moderate physical activity(HR=0.804,95％CI:0.666-0.971),high physical activity(HR=0.629,95％CI:0.504-0.785),overweight(HR=0.814,95％CI:0.711-0.933),obese(HR=0.844,95％CI:0.721-0.989).The risk of premature death among 1-2,3-4 and ≥5 interventionable risk factors at baseline was 1.365 times(95％CI:1.043-1.785),1.470 times(95％CI:1.124-1.922)and 1.839 times(95％CI:1.315-2.572)compared with those with 0,respectively.Conclusion The premature death of cardiovascular and cerebrovascular diseases in high-risk people aged 58 to 69 in Beijing is mainly cancer and cardiovascular and cerebrovascular diseases;emphasis should be placed on people with higher risk of premature death including men,low age group,low educational level,living in suburbs,smoking,unhealthy diet,and excessive blood pressure values.
Premature deathHigh-risk groups of cardio-cerebrovascular diseaseInfluencing factors
NETL
NSTL
万方数据
