Analysis on the death characteristics and disease burden of lung cancer in Gansu cancer registration areas from 2010 to 2019
Objective To understand the death level trend and disease burden of lung cancer in Gansu cancer registration areas from 2010 to 2019,and provide the reference for lung cancer prevention and control in Gansu Province.Methods Data were from the lung cancer death registration data in the cancer registration areas of Gansu Province from 2010 to 2019.The mortality rates and disease burden were calculated using SPSS 27.0 software.Joinpoint 5.2 software was used to analyze the change trend of rate,and to calculate the annual percentage change(APC).Results The lung cancer mortality rate in the cancer registration areas of Gansu Province from 2010 to 2019 was 23.71/105,the standardized mortality rates was 22.45/105 and 18.02/105 according to the Chinese population and the world standard population,respectively.The cumulative rate in the 0-74 age group was 2.19%,and the age-adjusted truncated rate in the 35-64 age group was 23.33/105.The mortality rate(31.21/105)of males was significantly higher than that(15.81/105)of females(P<0.05).The lung cancer mortality rate showed an increasing trend from 2010 to 2019(APC=7.97%,P<0.05).The mortality rate for lung cancer remained relatively low level in the 0-<45 years old group,but increased rapidly in the ≥45 years old group.Male,urban and rural areas all reached peak mortality between 80-84 years old,the female population reached the mortality peak in ≥85 years old group.The mortality rate for lung cancer in the ≥65 years old group showed a significantly increasing trend from 2010 to 2019(APC=5.66%,P<0.05).The potential years of life lost(PYLL)due to lung cancer in Gansu Province from 2010 to 2019 were 41 847 person-years,the standardized PYLL was 39 138 person-years.The average PYLL was 11.34 years,and the PYLL rate was 1.55‰,the standardized PYLL rate was 1.45‰.The potential years of work lost(WPYLL)due to lung cancer were 39 025 person-years,the standardized WPYLL were 36 746 person-years.The average WPYLL was 14.56 years,and the WPYLL rate was 1.41‰,the standardized WPYLL rate was 1.33‰.Conclusion Lung cancer disease burden in the cancer registration areas of Gansu Province is heavy.Targeted health education and lung cancer screening should be implemented to effectively reduce lung cancer mortality and disease burden.