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1990-2021年中国及分省儿童和青少年慢性病疾病负担分析

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目的 分析中国及其不同省份1990-2021年儿童和青少年主要慢性病疾病负担及变化情况,为优化儿童及青少年慢病防治工作提供科学依据.方法 数据来源于2021年全球疾病负担中国分省研究结果,利用死亡率、早死损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY)等指标分析1990-2021年中国0~<20岁儿童及青少年主要慢性病的疾病负担现状及其变化.采用SAS 9.4进行数据整理及分析.应用Joinpoint 5.2.0软件,采用对数线性回归模型计算平均年度变化百分比(AAPC),分析1990-2021年疾病负担长期变化趋势.结果 2021年中国儿童及青少年慢性病死亡率为15.1/10万,造成的DALY率为3952.9/10万.其中男性死亡率为17.2/10万,DALY率为4015.8/10万;女性死亡率为12.8/10万,DALY率为3 880.8/10万.分年龄分析结果显示,5岁以下儿童慢性病死亡率最高,为34.7/10万.与1990年相比,2021年中国儿童及青少年慢性病死亡率下降79.6%,前5位死因依次为肿瘤、心血管疾病、神经系统疾病、消化系统疾病、糖尿病和肾病;DALY率下降57.2%,男性和女性精神障碍、皮肤疾病、神经系统疾病和感觉器官疾病顺位均上升,精神障碍是导致DALY的首位疾病.不同地区儿童青少年死亡水平存在差异,西藏、青海和新疆等地死亡水平较高.结论 1990-2021年中国儿童和青少年慢性病的疾病负担总体呈下降趋势,但防控形势依然严峻.应采取针对性的预防策略,加强对儿童和青少年心理精神健康状况的关注,并强化针对5岁以下儿童的预防保健工作.
Burden of noncommunicable diseases among children and adolescents in China and its provinces from 1990 to 2021
Objective To analyze the disease burden and changes of major chronic diseases in children and adolescents in China and its provinces from 1990 to 2021,and provide the scientific basis for optimizing the prevention and treatment of chronic diseases in children and adolescents.Methods The data were from the results of China and provinces study in Global Burden of Disease 2021,the indicators of mortality,years of life lost(YLL),years lived with disability(YLD),and disability-adjusted life years(DALY)were used to analyze the current status and changes of major chronic disease burden of children and adolescents in China from 1990 to 2021.The data were analyzed using software SAS 9.4.Joinpoint 5.2.0 software was used to calculate the average annual percentage change(AAPC)through a log-linear regression model,the long-term trends in disease burden from 1990 to 2021 were analyzed.Results In 2021,the mortality rate and DALY rate of chronic diseases among children and adolescents in China were 15.1/105 and 3 952.9/105,respectively.The mortality rate and DALY rate in males were 17.2/1 05 and 4 015.8/105,respectively;the mortality rate and DALY rate in females were 12.8/105 and 3 880.8/1 05,respectively.Analysis by age group showed that the mortality(34.7/105)of children<5 years old was the highest.Compared with 1990,the mortality rate of chronic diseases among children and adolescents in China decreased by 79.6%in 2021.The top 5 causes of death were tumor,cardiovascular diseases,neurological diseases,digestive system diseases,diabetes and kidney diseases.The DALY rate decreased by 57.2%.The DALY ranking of mental disorders,skin and subcutaneous diseases,neurological disorders,and sensory organ disorders among males and females all rose,the first diseases leading to DALY was mental disorders.There was the difference of death level among children and adolescents in different regions,the age-standardized mortality in Xizang,Qinghai and Xinjiang were higher.Conclusion The burden of chronic diseases among children and adolescents in China from 1990 to 2021 showed decrease trend,but the prevention and control situation remains grim.Targeted prevention strategies should be adopted,the attention to the mental health status of children and adolescents should be strengthened,and the preventive and health care work for children<5 years old should be strengthened.

Children and adolescentsNoncommunicable diseasesMortalityDisability-adjusted life years

陈贺、王黎君、郎英旭、周梓芳、于昕辉、林琳、殷鹏、周脉耕、齐金蕾

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北京市西城区广内社区卫生服务中心,北京 100053

中国疾病预防控制中心慢性非传染性疾病预防控制中心生命登记与死因监测室,北京 100050

黑龙江省卫生健康管理服务评价中心统计科

儿童及青少年 慢性病 死亡率 伤残调整寿命年

2024

中国慢性病预防与控制
中华预防医学会,天津市疾病预防控制中心

中国慢性病预防与控制

CSTPCD北大核心
影响因子:1.093
ISSN:1004-6194
年,卷(期):2024.32(12)