Disease burden of anemia in China and its provinces from 1990 to 2021
Objective To analyze the burden of anemia and its changes in the Chinese population from 1990 to 2021,and provide the basis for formulating strategies and measures of anemia prevention and control.Methods The results of the 2021 Global Burden of Disease(GBD)for Chinese provinces study were used to analyze the anemia burden of China in 2021.The SAS 9.4 software and R 4.4.0 software were used to calculate the prevalence number,prevalence rate,age-standardized prevalence rate,years lived with disability(YLD),YLD rate and age-standardized YLD rate of anemia.The average annual percent change(AAPC)was calculated using Joinpoint 4.8.0.1 software.Results In 2021,the number of prevalence and YLD of anemia in China were 136.26 million and 3.02 million person-years,which decreased by 36.98%and 44.30%as compared with 1990,respectively.The age-standardized prevalence rate and age-standardized YLD rate of anemia showed a downward trend from 1990 to 2021(P<0.01),the anemia burden of female was higher than that of male.The age-standardized prevalence rate(19 013.34/105)in 1990 decreased to the age-standardized prevalence rate(8 913.09/105)in 2021,the drop was 53.12%,AAPC=-2.42%(P<0.01).The age-standardized YLD rate(494.04/105)in 1990 decreased to 200.83/105 in 2021,the drop was 59.35%,AAPC=-2.86%(P<0.05).In 2021,the anemia number(395.20 ten thousand cases)of male children<5 years old was the greatest;the anemia number(972.10 ten thousand cases)of females(30-34 years old)was the greatest.The prevalence rates of anemia in males and females increased with age,but the prevalence rate of anemia in females(20-49 years old)significantly elevated.In 2021,3 top provinces with the highest age-standardized prevalence rate of anemia were Xizang(14 839.08/105),Xinjiang(11 860.15/105)and Qinghai(11 730.70/105),respectively;3 top provinces with the highest age-standardized YLD rate of anemia were Xizang(429.68/105),Qinghai(316.75/105)and Xinjiang(306.52/105),respectively.As compared with 1990,the age-standardized prevalence rates and age-standardized YLD rates of anemia in 33 provinces all decreased.Conclusion From 1990 to 2021,the disease burden of anemia in China showed the downtrend,the anemia burden of female was higher than that of male.The age-standardized prevalence rate and age-standardized YLD rate in all provinces decreased,but there was differences.
AnemiaPrevalence rateYears lived with disabilityDisease burden