中国免疫学杂志2024,Vol.40Issue(3) :668-672,封3-封4.DOI:10.3969/j.issn.1000-484X.2024.03.039

新型冠状病毒感染相关的儿童多系统炎症综合征

Multisystem inflammatory syndrome in children related with COVID-19 infection

胡小燕 罗军 向金波 孙飞
中国免疫学杂志2024,Vol.40Issue(3) :668-672,封3-封4.DOI:10.3969/j.issn.1000-484X.2024.03.039

新型冠状病毒感染相关的儿童多系统炎症综合征

Multisystem inflammatory syndrome in children related with COVID-19 infection

胡小燕 1罗军 1向金波 1孙飞1
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作者信息

  • 1. 三峡大学第二临床医学院,宜昌 443000
  • 折叠

摘要

儿童多系统炎症综合征是一种与严重急性呼吸综合征冠状病毒2感染相关,可累及多系统损害的疾病,休克、心功能不全、胃肠道症状、炎症和心脏损伤标志物显著升高及SARS-CoV-2血清学检测结果呈阳性为其特征.虽然其临床特征与川崎病有所重叠,但该病好发于较大年龄的儿童及青少年,且大多数患者需要经过重症监护及多种免疫调节剂治疗,目前该病的发病机制及远期预后尚需进一步研究.

Abstract

Multisystem inflammatory syndrome in children is a disease related with severe acute respiratory syndrome corona-virus 2 infection,which can involve multiple system damage.Most cases included features of shock,cardiac dysfunction,gastrointestinal symptoms,significantly elevated markers of inflammation and cardiac damage,and positive test results for SARS-CoV-2 by serology.Although its clinical features overlap with Kawasaki disease,it is more likely to occur in older children and adolescents,and most of them need to be treated with intensive care and a variety of immunomodulators.At present,the pathogenesis and long-term prognosis of the disease need to be further studied.

关键词

儿童多系统炎症综合征/严重急性呼吸综合征冠状病毒2/新型冠状病毒感染/川崎病

Key words

Multisystem inflammatory syndrome in children/Severe acute respiratory syndrome coronavirus 2/Coronavirus disease 2019/Kawasaki disease

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基金项目

湖北陈孝平科技发展基金会科研项目(CXPJJH121002-202128)

出版年

2024
中国免疫学杂志
中国免疫学会,吉林省医学期刊社

中国免疫学杂志

CSTPCD北大核心
影响因子:0.926
ISSN:1000-484X
参考文献量60
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