新型冠状病毒感染相关的儿童多系统炎症综合征
Multisystem inflammatory syndrome in children related with COVID-19 infection
胡小燕 1罗军 1向金波 1孙飞1
作者信息
- 1. 三峡大学第二临床医学院,宜昌 443000
- 折叠
摘要
儿童多系统炎症综合征是一种与严重急性呼吸综合征冠状病毒2感染相关,可累及多系统损害的疾病,休克、心功能不全、胃肠道症状、炎症和心脏损伤标志物显著升高及SARS-CoV-2血清学检测结果呈阳性为其特征.虽然其临床特征与川崎病有所重叠,但该病好发于较大年龄的儿童及青少年,且大多数患者需要经过重症监护及多种免疫调节剂治疗,目前该病的发病机制及远期预后尚需进一步研究.
Abstract
Multisystem inflammatory syndrome in children is a disease related with severe acute respiratory syndrome corona-virus 2 infection,which can involve multiple system damage.Most cases included features of shock,cardiac dysfunction,gastrointestinal symptoms,significantly elevated markers of inflammation and cardiac damage,and positive test results for SARS-CoV-2 by serology.Although its clinical features overlap with Kawasaki disease,it is more likely to occur in older children and adolescents,and most of them need to be treated with intensive care and a variety of immunomodulators.At present,the pathogenesis and long-term prognosis of the disease need to be further studied.
关键词
儿童多系统炎症综合征/严重急性呼吸综合征冠状病毒2/新型冠状病毒感染/川崎病Key words
Multisystem inflammatory syndrome in children/Severe acute respiratory syndrome coronavirus 2/Coronavirus disease 2019/Kawasaki disease引用本文复制引用
基金项目
湖北陈孝平科技发展基金会科研项目(CXPJJH121002-202128)
出版年
2024