Min structure and mutation of SARS-CoV-2 S protein and potential mechanism of S protein-induced disease
SARS-CoV-2 caused severe threat to people's health all over the world,and has attracted widespread attention from researchers.The spike protein of SARS-CoV-2 is a key structure mediating the binding of the virus to its host.Therefore,it is im-portant to elucidate the mechanism of spike protein-induced immune responses.We've reviewed the structure of spike protein from al-pha to omicron variant,as well as the potential mechanisms of spike-induced in multiple systems,so as to provide a reference for dis-ease prevention and treatment.