B细胞抗原表位鉴定方法的研究进展
Advances on research of B-cell epitopes mapping methods
伍春平 1尹苗 1陈希文1
作者信息
- 1. 四川生猪重大疫病监测与防控工程研究中心,绵阳 621000
- 折叠
摘要
抗原表位是抗原决定其抗原性的基础,是诱导机体产生免疫应答的最小功能单位.B细胞抗原表位研究对于新型疫苗和治疗性药物的研发以及诊断试剂的开发具有重要意义.本文总结了近几年应用B细胞抗原表位研究的技术,并分析了各种技术的优缺点.
Abstract
Epitopes are the basis of antigenicity and the smallest functional unit to induce immune response.Identification of B-cell epitopes is of great significance for the development of new vaccines and therapeutic drugs as well as diagnostic reagents.In this paper,the methods applied in the study of B-cell epitopes mapping in recent years are reviewed and their advantages and shortages are analyzed.
关键词
B细胞抗原表位/免疫/筛选鉴定Key words
B-cell epitopes/Immune/Screening and mapping引用本文复制引用
基金项目
四川省重点研发计划(2023YFN0045)
出版年
2024
国家科技期刊平台
NSTL
万方数据