中国免疫学杂志2024,Vol.40Issue(7) :1548-1552.DOI:10.3969/j.issn.1000-484X.2024.07.034

柯里拉京在肝炎、肝纤维化和肝癌中的作用及机制研究进展

Advances in role and mechanism of corilagin in hepatitis,liver fibrosis and hepatic carcinoma

刘新羽 史晓睿 张惠 闫风连
中国免疫学杂志2024,Vol.40Issue(7) :1548-1552.DOI:10.3969/j.issn.1000-484X.2024.07.034

柯里拉京在肝炎、肝纤维化和肝癌中的作用及机制研究进展

Advances in role and mechanism of corilagin in hepatitis,liver fibrosis and hepatic carcinoma

刘新羽 1史晓睿 1张惠 1闫风连1
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作者信息

  • 1. 济宁医学院基础医学院免疫学与分子医学研究所,济宁 272067
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摘要

柯里拉京是多种中药的主要活性成分,具有广泛的药理作用,在肝炎、肝纤维化和肝癌等多种肝脏疾病中均具有保护作用,因此在治疗肝脏相关疾病方面显示出广阔的应用前景,但应用过程中暴露的问题促使研究者进一步探索柯里拉京的潜在作用.本文总结了近年柯里拉京在肝炎、肝纤维化和肝癌中的作用及机制研究进展,以期为后续研究和应用提供参考.

Abstract

Corilagin is one of major bioactive compounds in many Chinese medical plants,which has been demonstrated to exhibit multiple pharmacological activities.Hepatoprotective effects of corilagin have been reported in some liver diseases,such as hepatitis,liver fibrosis and hepatic carcinoma.Therefore,corilagin has shown broad prospects in treatment of liver diseases.However,problems exposed in application process prompted researchers to further explore potential role of corilagin.Research progress of the role and mechanism of corilagin in hepatitis,liver fibrosis and hepatic carcinoma are summarized to provide reference for subsequent studies.

关键词

肝脏疾病/柯里拉京/肝炎/肝纤维化/肝癌/机制

Key words

Liver disease/Corilagin/Hepatitis/Liver fibrosis/Hepatic carcinoma/Mechanism

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基金项目

国家自然科学基金面上项目(82171810)

山东省医药卫生科技发展计划项目(202002070949)

山东省大学生创新训练计划项目(S202110443039)

国家级大学生创新训练计划项目(S202010443005)

出版年

2024
中国免疫学杂志
中国免疫学会,吉林省医学期刊社

中国免疫学杂志

CSTPCDCSCD北大核心
影响因子:0.926
ISSN:1000-484X
参考文献量2
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