3型固有淋巴细胞在慢性炎症性疾病中的作用
Role of type-3 innate lymphoid cell in chronic inflammatory diseases
徐峥 1于明凯 1张峰波 2丁剑冰1
作者信息
- 1. 新疆医科大学基础医学院免疫学教研室,乌鲁木齐 830011
- 2. 新疆医科大学第一附属医院,乌鲁木齐 830054
- 折叠
摘要
3型固有淋巴细胞(ILC3)分化于淋巴祖细胞,在机体内分布广泛,是连接固有免疫和适应性免疫的桥梁.既往研究认为ILC3主要参与肠道免疫调节,而最新研究表明除在肠道疾病中的作用外,ILC3还参与多种慢性炎症性疾病发生发展.本文就ILC3在慢性炎症性疾病中的作用进行综述.
Abstract
Type-3 innate lymphoid cell(ILC3)differentiate into lymphocyte progenitor cells and widely distributed in body,serving as a bridge between innate immunity and adaptive immunity.Previous studies believed that ILC3 was mainly involved in intesti-nal immune regulation,however,the latest studies have shown that,in addition to its role in intestinal diseases,ILC3 can also partici-pate in occurrence and development of a variety of chronic inflammatory diseases.This article reviews role of ILC3 in chronic inflamma-tory diseases.
关键词
3型固有淋巴细胞/细胞因子/免疫调节/慢性炎症性疾病Key words
Type-3 innate lymphoid cell/Cytokines/Immune regulation/Chronic inflammatory disease引用本文复制引用
基金项目
国家自然科学基金(81660343)
国家自然科学基金(81960373)
出版年
2024
国家科技期刊平台
NSTL
万方数据