首页|3型固有淋巴细胞在慢性炎症性疾病中的作用

3型固有淋巴细胞在慢性炎症性疾病中的作用

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3型固有淋巴细胞(ILC3)分化于淋巴祖细胞,在机体内分布广泛,是连接固有免疫和适应性免疫的桥梁.既往研究认为ILC3主要参与肠道免疫调节,而最新研究表明除在肠道疾病中的作用外,ILC3还参与多种慢性炎症性疾病发生发展.本文就ILC3在慢性炎症性疾病中的作用进行综述.
Role of type-3 innate lymphoid cell in chronic inflammatory diseases
Type-3 innate lymphoid cell(ILC3)differentiate into lymphocyte progenitor cells and widely distributed in body,serving as a bridge between innate immunity and adaptive immunity.Previous studies believed that ILC3 was mainly involved in intesti-nal immune regulation,however,the latest studies have shown that,in addition to its role in intestinal diseases,ILC3 can also partici-pate in occurrence and development of a variety of chronic inflammatory diseases.This article reviews role of ILC3 in chronic inflamma-tory diseases.

Type-3 innate lymphoid cellCytokinesImmune regulationChronic inflammatory disease

徐峥、于明凯、张峰波、丁剑冰

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新疆医科大学基础医学院免疫学教研室,乌鲁木齐 830011

新疆医科大学第一附属医院,乌鲁木齐 830054

3型固有淋巴细胞 细胞因子 免疫调节 慢性炎症性疾病

国家自然科学基金国家自然科学基金

8166034381960373

2024

中国免疫学杂志
中国免疫学会,吉林省医学期刊社

中国免疫学杂志

CSTPCD北大核心
影响因子:0.926
ISSN:1000-484X
年,卷(期):2024.40(9)