Research progress on therapeutic potential of mesenchymal stem cells in recurrent spontaneous abortion
Recurrent spontaneous abortion(RSA)is one of the most common complications in early pregnancy,affecting about 2%～5%of women of childbearing age,and its incidence is increasing year by year,which not only affects women's physical and mental health,but also causes a heavy economic burden to the society and the family.Mesenchymal stem cells(MSCs)are a class of non-hematopoietic adult multipotent stem cells derived from mesodermal mesenchymal cells of a variety of tissues.They have the characteristics of multi-directional differentiation and self-renewal,and can improve the fertility outcome of RSA patients,which has become a research hotspot in recent years.Therefore,this paper explores the roles and mechanisms of MSCs from different sources in improving pregnancy outcomes in RSA patients,and analyzes their research status and existing problems.
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