In order to explore the effects of different fertilization treatments on the growth,yield and fruit quality of guava,no fertilization(CK),single application of organic fertilizer 15 kg/plant(T1),conventional application of compound fertilizer 2 kg/plant(T2),organic fertilizer 15 kg/plant+compound fertilizer 1.6 kg/plant(T3),organic fertilizer 15 kg/plant+compound fertilizer 1.2 kg/plant(T4)and organic fertilizer 15 kg/plant+compound fertilizer 0.8 kg/plant(T5)were set up.The results showed that the branch length of T3 increased by 15.75%compared with T2,the longitudinal diameter of the two batches of fruits increased by 7.73%and 7.49%compared to T2,and the transverse diameter increased by 9.57%and 9.97%.The average single fruit mass of two batches of fruits treated with T3 increased by 18.80%and 21.36%compared to T2.The T3 and T4 had a better effect on improving fruit quality.Among them,the vitamin C content of the two batches of fruits treated with T3 increased by 19.98%and 10.80%compared to T2 treatment,and the soluble solids content increased by 19.61%and 11.30%.The total sugar content of two batches of fruits treated with T4 increased by 25.97%and 27.18%compared to T2,the reducing sugar content increased by 27.24%and 36.27%,and the crude fiber content decreased by 24.19%and 24.43%.To sum up,compared with the treatment of no fertilization or single fertilization,increasing the application of organic fertilizer by 15 kg and adding 1.2-1.6 kg of compound fertilizer per plant have a more significant promotion effect on improving the yield and quality of guava.