Study on Mycoplasma bovis Vaccine Immunization Program and Dynamics of Maternal Antibodies
In order to evaluate different doses of mycoplasma bovine inactivated aluminum hydroxide adjuvant vaccine for pregnant cows immune antibody immunity and immune effect,this test choose prenatal 30～15 d perinatal cows,randomly divided into 7 groups,each group 10 cattle,15 d interval,using different doses,regular collection colostrum and calf serum,using the established method of indirect ELISA to detect the colostrum whey and the antibody elimination.The results showed that the vaccine is safe and reliable and immunization with pregnant cow vaccine with the extension of postpartum time,the antibody values were below 0.3;the antibody in group A was the lowest,group B,C and D were lower than groups E and F;group E and F were higher,with no difference between the two.After colostrum feeding by calves with different doses of vaccine,mycoplasma IgG antibody in calf serum reached the highest 24h after birth,and the antibody titer decreased.In groups A,B and C,the antibody level was higher than group A,B,C,and lower than Group E and F;group E and F had higher levels and maintained for A long time.The results provide a scientific basis for the development of mycoplasma vaccine.
万方数据
维普
