摘要
寻找影响哺乳动物目标性状的数量性状位点(QTL)通常仅限于常染色体,X染色体变异尚未被纳入用于估计动物育种值的基因组预测方程中.而X染色体作为牛第二大的染色体,具有重要的生物学意义.随着基因组工作的深入,对X染色体上遗传变异的功能性研究也越来越多,分析包含X染色体基因组标记信息可以改善基因组育种值的预测.本研究综述了X染色体上的基因与奶牛产奶、繁殖、健康、体型和生产寿命等性状关联分析的研究进展,以期为提高奶牛生产性能的研究提供帮助.
Abstract
The search for quantitative trait loci(QTL)affecting traits of interest in mammals is usually limited to autosomes,and X chromosome variation has not yet been included in genomic prediction equations used to estimate animal breeding values.In contrast,the X chromosome,as the second largest chromosome in cattle,bears important biological significance,and as genomic work has intensified,functional studies of genetic variation on the X chromosome have increased,and the inclusion of X chromosome genomic marker information in analyses can improve the prediction of genomic breeding values.In this study,we reviewed the progress of research on association analysis of genes on the X chromosome with traits such as milk production,reproduction,health,body size and productive longevity in dairy cows,with a view to providing assistance in research to improve the production performance of dairy cows.
国家科技期刊平台
NSTL
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