Advances in the role of annexin A1 in cerebral ischemia-reperfusion injury
Cerebral ischemia-reperfusion injury is a secondary and inevitable pathophysiological change in the process of vascular recanalization in acute ischemic stroke,which can lead to neuronal damage,affect cognitive and behavioral functions,and even cause death.Inflammatory response is one of the important mechanisms leading to cerebral ischemia-reperfusion injury.Annexin A1(ANXA1)is a powerful physiological anti-inflammatory protein.The authors reviews the relationship between ANXA1 and cerebral ischemia-reperfusion injury in recent years,in order to provide reference for subsequent research.
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