膜联蛋白A1在脑缺血-再灌注损伤中作用的研究进展
Advances in the role of annexin A1 in cerebral ischemia-reperfusion injury
汤子豪 1孙军2
作者信息
- 1. 310053 杭州,浙江中医药大学第二临床医学院
- 2. 浙江省温州市中心医院泛血管疾病管理中心实验室
- 折叠
摘要
脑缺血-再灌注损伤是急性缺血性卒中血管再通治疗过程中继发且不可避免的病理生理变化,可导致神经元受损,影响认知功能和行为功能,甚至发生死亡.炎症反应是导致脑缺血-再灌注损伤的重要机制之一.膜联蛋白A1是一种强大的生理性抗炎症蛋白质,作者对近年来膜联蛋白A1与脑缺血-再灌注损伤的关系进行综述,以期为后续研究提供参考.
Abstract
Cerebral ischemia-reperfusion injury is a secondary and inevitable pathophysiological change in the process of vascular recanalization in acute ischemic stroke,which can lead to neuronal damage,affect cognitive and behavioral functions,and even cause death.Inflammatory response is one of the important mechanisms leading to cerebral ischemia-reperfusion injury.Annexin A1(ANXA1)is a powerful physiological anti-inflammatory protein.The authors reviews the relationship between ANXA1 and cerebral ischemia-reperfusion injury in recent years,in order to provide reference for subsequent research.
关键词
膜联蛋白A1/再灌注损伤/炎症/综述Key words
Annexin A1/Reperfusion injury/Inflammation/Review引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据