Research progress on biomarkers of futile recanalization after endovascular thrombectomy in ischemic stroke
Acute ischemic stroke has a high mortality and disability rate,posing a serious threat to human health.Endovascular treatment is now a first-line approach for acute ischemic stroke.However,some patients achieving successful revascularization(modified thrombolysis in cerebral infarction grade 2b or 3)still have poor neurological outcomes(midified Rankin scale score>2)90 days after the procedure,a phenomenon known as futile recanalization.This review aims to summarize the mechanisms and baseline characteristics,blood markers,and imaging markers of futile recanalization,helping clinicians identify and detect at-risk patients early.This will provide insights for the prevention and management of futile recanalization.