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鱼类血细胞及其免疫防御功能研究进展

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鱼类血细胞是机体免疫的重要组成部分，不仅参与吞噬、分泌，还参与机体损伤修复、免疫防御等生理过程，其对自身生理状态变化和外界环境因子刺激均十分敏感，因此在指示和维持鱼体生理稳态等方面发挥重要作用。本文综述了近年来国内外关于鱼类血液和血细胞及其免疫防御功能的研究进展，包括鱼类血液组成、血细胞发生、分化及相关免疫防御机制等。本综述旨在提高对鱼类血液免疫防御系统及其分子作用机制的理解，为进一步挖掘鱼类血液免疫防御相关分子标记、筛选鱼类抗病抗逆分子表型等提供参考。
Research Advances on Fish Blood Cells and Immune Defense Functions
Fish blood cells are important part in fish body immunity.They participate in many physiological activities,such as body phagocytosis,secretion,damage repair,defense and others.They are sensitive to changes in their own physiological state as well as to the stimulation of external environmental factors.Blood cells play an important role in indicating and maintaining the physiological homeostasis of fish.Based on recent research reports of domestic and international developments,this paper investigated the progress of fish blood,blood cells and their immune defense functions,and reviewed the blood composition,blood cell genesis,differentiation and related immune defense mechanisms of fish.This review is helpful to deepen the understanding of fish blood immune defense system and its related molecular mechanism,and provides references for further exploration of molecular markers related to fish blood immune defense and screening of molecular phenotypes of fish disease and stress resistance.

fishfish bloodblood cellimmune cellcell differentiationimmune defensephysiological homeostasismolecular mechanisms of action

张美燕、朱伟娟、刘志刚、曹建萌、王章、卢迈新、可小丽

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中国水产科学研究院珠江水产研究所/农业部热带亚热带水产资源利用与养殖重点实验室/广东省水产动物免疫技术重点实验室,广州 510380

上海海洋大学水产与生命学院,上海 201306

鱼类 鱼类血液 血细胞 免疫细胞 细胞分化 免疫防御 生理稳态 分子作用机制

现代农业产业技术体系专项资金国家自然科学基金广东省基础与应用基础研究基金2022年水产种业体系建设项目

CARS-46321028342021A1515010852粤财农2022119号

2024

中国农学通报
中国农学会

中国农学通报

CSTPCD
影响因子：0.891
ISSN：1000-6850
年,卷(期)：2024.40(26)