Cyprinid herpesvirus Ⅱ(CyHV-Ⅱ)is the cause of(goldfish haematopoietic necrosis,GFHN),which can infect goldfish,Crucian carp and their hybrid at any developmental stage.It is a highly contagious disease with high mortality rate,which has caused huge economic losses to goldfish and Crucian carp aquaculture in China.The research and development of fish vaccine is the most effective way to prevent and treat the disease.The research and development progress of inactivated CyHV-Ⅱ vaccine,subunit vaccine,nucleic acid vaccine,live vector vaccine and Nano-delivered vaccines were reviewed in this paper.Furthermore,the application prospect of fish vaccine nano materials was discussed,which would provide new technical methods and new ideas for the prevention and treatment of goldfish herpes disease and fish vaccine research.
关键词
鲤疱疹病毒二型(CyHV-Ⅱ)/免疫途径/纳米材料/疫苗类型
Key words
Cyprinid herpesvirus Ⅱ(CyHV-Ⅱ)/immunization route/nano materials/vaccine type
维普
万方数据