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局部晚期甲状腺癌的成因分析与临床启示

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虽然甲状腺癌预后总体良好,但部分甲状腺癌患者经过初期规范治疗后,仍可能进入持续、复发或远处转移状态.其中侵袭性局部晚期甲状腺癌(LATC)患者的预后较差,是该病致死的主要原因.对LATC的成因分析显示,大部分LATC由分化型甲状腺癌演化而来.术前评估的局限性、治疗强度的逐渐降级和热消融治疗的推广是LATC成因的影响因素.有必要对低危甲状腺癌进行早期规范管理,防止LATC的形成.
Etiological analysis and clinical implications of locally advanced thyroid cancer
Although the overall prognosis of thyroid cancer is favorable,some patients may still experience persistent,recurrent,or distant metastatic disease after initial standard treatment. Among them,patients with locally advanced thyroid cancer (LATC) have a poorer prognosis,making it a major cause of mortality in thyroid cancer. Analysis of etiology of LATC reveals that most LATC cases arise from the progression of differentiated thyroid cancer. Contributing factors include limitations in preoperative assessment,gradual downgrading of treatment intensity,and the widespread adoption of thermal ablation therapies. Therefore,early standardized management of low-risk thyroid cancer is essential to prevent the development of LATC.

Thyroid NeoplasmsThyroid Cancer,PapillaryEarly Detection of Cancer

程若川、刘文、董治中

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昆明医科大学第一附属医院甲状腺疾病诊治中心,云南昆明 650032

甲状腺肿瘤 甲状腺癌,乳头状 癌症早期检测

2024

中国普通外科杂志
中南大学

中国普通外科杂志

CSTPCD北大核心
影响因子:1.623
ISSN:1005-6947
年,卷(期):2024.33(11)