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急性胰腺炎中医药治疗的靶点与机制

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急性胰腺炎(acute pancreatitis,AP)是临床常见急腹症,发病率逐年升高,目前仍缺乏有效的治疗方法.中医药作为中国传统医学宝库,已被应用于治疗AP几十年,具有良好的治疗效果.目前临床试验及基础实验研究表明,中药具有抑制胰酶活性、抗炎、促进胃肠道动力等作用,可延缓AP病情进展,改善临床症状,减少相关并发症,降低病死率.因此,中医药治疗AP具有较大的临床价值.笔者结合相关研究进展和团队临床实践结果,对中医药治疗AP的靶点及机制要点进行归纳总结.
Target and mechanism of traditional Chinese medicine in acute pancreatitis
Acute pancreatitis(AP)is a common clinical emergency of the abdomen with increasing incidence and lack of effective treatment.Traditional Chinese medicine,as a treasure of the Chinese people,has been used in the treatment of AP for decades with favorable therapeutic effects.Currently,clinical trials and experimental studies have shown that traditional Chinese medicine has the effects of inhibiting pancreatic enzyme activity,anti-inflammation,promoting gastrointestinal dynamics,as well as delaying the progress of AP,improving clinical symptoms,reducing related complications,and reducing the mortality rate.Therefore,traditional Chinese medicine has considerable clinic value in treating AP.Based on the related research progress and clinical practice of our team,the authors summarized the targets and mechanism of traditional Chinese medicine in treating AP.

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曹菲、陈炜炜

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扬州大学临床医学院消化内科(江苏扬州 225200)

急性胰腺炎 中医药 靶点 机制

国家自然科学基金江苏省333高层次人才培养工程江苏省六大人才高峰工程

82004291WSN-325

2024

中国普外基础与临床杂志
四川大学华西医院

中国普外基础与临床杂志

CSTPCD
影响因子:0.858
ISSN:1007-9424
年,卷(期):2024.31(2)
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