肝部分切除术患者加速康复外科失败的影响因素分析
Analysis of risk factors for failure of enhanced rehabilitation surgery in patients undergoing partial hepatectomy
李佳霏 1任秋平 2叶佳怡 1陈雨文 1李卡1
作者信息
- 1. 四川大学华西护理学院/四川大学华西医院(成都 610041)
- 2. 四川大学华西医院普外科肝脏外科病房/四川大学华西护理学院(成都 610041)
- 折叠
摘要
目的 探索肝部分切除手术后加速康复外科失败的影响因素.方法 回顾性收集2019年1月至12月期间在四川大学华西医院肝脏外科行肝部分切除术同时采用加速康复外科(enhanced recovery after surgery,ERAS)进行围手术期管理的344例患者的临床资料.采用单因素及多因素logistic回归分析来探索肝部分切除术后加速康复外科失败的危险因素.结果 344例患者被纳入研究,其中ERAS失败44例,ERAS成功300例.多因素回归分析结果表明:合并慢性疾病[OR=2.32,95%CI(1.07,4.93),P=0.03]和术中补液量≤2475 mL[OR=2.16,95%CI(1.06,4.42),P=0.03]是ERAS方案失败的危险因素.结论 合并慢性疾病和术中补液量≤2 475 mL是肝部分切除术后ERAS失败的危险因素,影响患者预后.
Abstract
Objective To explore the risk factors for failure of enhanced recovery after surgery(ERAS)in partial hepatectomy.Methods A retrospective analysis was performed on 344 patients who underwent partial hepatectomy at the Division of Liver Surgery,Department of General Surgery in West China Hospital of Sichuan University from January 2019 to December 2019.All patients were treated with ERAS after partial hepatectomy.Univariate and multivariate logistic regression analysis were used to evaluate the risk factors associated with failure of the ERAS after partial hepatectomy.Results A total of 344 patients were included in the study,including 44 patients in the ERAS failure group and 300 patients in the ERAS success group.Multivariate logistic regression showed that combined with chronic diseases[OR=2.32,95%CI(1.07,4.93),P=0.03]and intraoperative fluid replacement volume ≤2 475 mL[OR=2.16,95%CI(1.06,4.42),P=0.03]were risk factors for failure of ERAS.Conclusion Chronic diseases and intraoperative fluid volume ≤2 475 mL are risk factors for the failure of ERAS after partial hepatectomy and can affect prognosis.
关键词
加速康复外科/失败/肝部分切除术/危险因素Key words
enhanced recovery after surgery/failure/partial hepatectomy/risk factor引用本文复制引用
基金项目
国家自然科学基金区域创新发展联合基金重点项目资助(U22A20334)
四川省自然科学基金面上项目(2023NSFSC0542)
出版年
2024