Research progress of biomarkers related to deep vein thrombosis
Objective To summarize the new biomarkers of deep venous thrombosis(DVT)and their research progress,so as to provide new ideas for the prevention,diagnosis and treatment of DVT.Method The literature about biomarkers of DVT in recent 5 years was reviewed and summarized.Results According to the results of literature review,a variety of common DVT biomarkers such as serum microrna,fibrin monomer,neutrophil capture net,and E-selectin were sorted out,but most of them had not been used in clinical DVT management.At present,the clinical diagnosis of DVT required the combination of positive D-dimer test and positive imaging examination,and there was no single biomarker for the diagnosis of DVT.Conclusions Biomarkers are valuable in the diagnosis and treatment of DVT,but their sensitivity and specificity need to be optimized.Therefore,finding biomarkers with more diagnostic value is one of the future directions.At the same time,we also can consider fully combined with a variety of existing biomarkers,to improve the efficiency to the diagnosis of DVT.
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