中国普外基础与临床杂志2024,Vol.31Issue(12) :1413-1418.DOI:10.7507/1007-9424.202409124

以外科手术为核心的肝细胞癌综合治疗策略

Comprehensive treatment strategy for hepatocellular carcinoma centered on surgical intervention

游逾 刘作金 龚建平
中国普外基础与临床杂志2024,Vol.31Issue(12) :1413-1418.DOI:10.7507/1007-9424.202409124

以外科手术为核心的肝细胞癌综合治疗策略

Comprehensive treatment strategy for hepatocellular carcinoma centered on surgical intervention

游逾 1刘作金 1龚建平1
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作者信息

  • 1. 重庆医科大学附属第二医院肝胆外科(重庆 400010)
  • 折叠

摘要

肝细胞癌是全球高发的恶性肿瘤之一,尽管手术是患者获得长期生存的关键手段,但多数患者在初次确诊时无法进行手术,整体治疗效果欠佳.笔者就目前肝细胞癌的治疗策略,特别是以手术为核心的综合治疗方案进行了阐述,探讨了在多学科诊疗模式下开展术前转化、微创手术、术后辅助等综合治疗的现状和进展.通过合理的综合治疗策略,有望改善肝细胞癌患者的治疗效果和生活质量.

Abstract

Hepatocellular carcinoma(HCC)is one of the most prevalent malignant tumors worldwide.Although surgery remains the key approach for achieving long-term survival,the majority of patients are ineligible for surgery at the time of initial diagnosis,resulting in suboptimal overall treatment outcomes.This paper reviews the current treatment strategies for HCC,with a particular focus on comprehensive treatment plans centered around surgery.It explores the status and advancements in multidisciplinary treatment approaches,including preoperative conversion therapy,minimally invasive surgery,and postoperative adjuvant therapies.Through the adoption of rational comprehensive treatment strategies,it is anticipated that the therapeutic outcomes and quality of life for HCC patients can be improved.

关键词

肝细胞癌/肝切除/肝移植/靶向治疗/免疫检查点抑制剂

Key words

hepatocellular carcinoma/liver resection/liver transplantation/targeted therapy/immune checkpoint inhibitors

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出版年

2024
中国普外基础与临床杂志
四川大学华西医院

中国普外基础与临床杂志

CSTPCD
影响因子:0.858
ISSN:1007-9424
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