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肝细胞癌转化治疗研究进展

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原发性肝癌(以下简称肝癌)是我国第4大常见癌症和第2大癌症死亡原因,肝细胞癌(hepatocellular carcinoma,HCC)占肝癌的75%~85%,超过半数的HCC患者就诊时已处于疾病中晚期,不适合接受手术切除,转化治疗可为一些不可切除患者提供手术切除的机会.随着肝癌非手术治疗的进步、综合治疗理念的重视以及不断涌现的临床研究成果,肝癌转化治疗已在我国肝癌治疗临床实践中成为常见临床路径.笔者就HCC转化治疗研究进展进行综述,分析其方法、疗效、安全性和手术时机,为HCC转化治疗策略的临床实践和研究提供思路.
Research progress of conversion therapy in hepatocellular carcinoma
Primary liver cancer(hereinafter referred to as liver cancer)is the fourth most common cancer and second leading cause of cancer-related deaths of China.Hepatocellular carcinoma(HCC)accounts for 75%to 85%of liver cancers,more than half of patients with HCC present at an advanced stage where surgery is not suitable.Conversion therapy can provide the opportunity for some unresectable patients to realize surgical resection.With the progress of non-surgical treatments for liver cancer,increased emphasis on comprehensive treatment approaches,and continuous clinical research outcome,conversion therapy of liver cancer has become a common clinical pathway in treatment practice in our country.This paper summarizes the progress in research on conversion therapy for HCC,analyzing its methods,efficacy,safety,and timing of surgery,to provide insights for the clinical practice and research of conversion treatment in HCC.

hepatocellular carcinomaconversion therapyunresectable

蓝晨露、曾智明、朱广志、彭涛

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广西医科大学第一附属医院肝胆外科(南宁 530021)

广西医科大学第一附属医院肿瘤内科(南宁 530021)

广西消化道肿瘤加速康复外科基础研究重点实验室(南宁 530021)

肝细胞癌 转化治疗 不可切除

2024

中国普外基础与临床杂志
四川大学华西医院

中国普外基础与临床杂志

CSTPCD
影响因子:0.858
ISSN:1007-9424
年,卷(期):2024.31(12)