摘要
新型冠状病毒感染后病症(PCC)定义为在有可能或确诊严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)感染的 3 个月后,出现无法用其他诊断来解释的、至少持续 2 个月的症状.PCC是生物学因素、心理学因素及社会文化因素综合作用的结果,具有患病数较多、发病机制复杂、症状多样、长期照护需求大的特点.PCC的诊断被视为排除性诊断,可划分为"非重度COVID-19 多器官后遗症""肺纤维化后遗症""肌痛性脑脊髓炎或慢性疲劳综合征""体位性直立性心动过速综合征""重症监护后综合征"和"医学或临床后遗症"6 种亚型,在整体性评估的基础上,可在多学科协作的模式下,通过药物、膳食、运动、心理干预、患者教育等方法进行治疗和照护.
Abstract
Post-COVID-19 condition is defined as the presence of symptoms that cannot be explained by other diagnoses,lasting for at least 2 months,occurring three months after a possible or confirmed SARS-CoV-2 infection.It is the result of a complex interplay of biological,psychological,and sociocultural factors,characterized by a high number of affected individuals,complex pathogenesis,diverse symptoms,and a significant need for long-term care.The diagnosis is considered exclusionary and can be classified into six subtypes,including non-severe COVID-19 multiorgan sequelae,pulmonary fibrosis sequelae,myalgic encephalomyelitis or chronic fatigue syndrome,postural orthostatic tachycardia syndrome,post-intensive care syndrome,and medical or clinical sequelae.Based on comprehensive evaluation,treatment and care can be provided through a multidisciplinary approach involving medication,diet,exercise,psychological interventions,patient education,and other methods.
基金项目
国家重点研发计划(2021YFF0604000)
广东省医学科学技术研究基金项目(B2022274)
广东省医学科学技术研究基金项目(B2023307)