Intestinal stem cells are an important part of maintaining the stability of intestinal barrier function,which is closely related to intestinal homeostasis,intestinal epithelial renewal,and repair of intestinal damage.Normal physiological activities of the human body cannot be separated from energy intake and metabolism,and the differentiation fate of stem cells is affected by energy metabolism,and impaired intestinal barrier is associated with the development of many intestinal diseases.Therefore,this paper focuses on intestinal stem cells,takes energy metabolism and metabolites as the background to investigate how energy metabolism and metabolites regulate the function and activity of stem cells,thus regulating the function of intestinal barrier and providing ideas for the treatment of various intestinal diseases;in addition,with the in-depth research of modern medical science in protecting intestinal barrier,the theory of traditional Chinese medicine(TCM)that cares for spleen and stomach is gradually showing its scientific validity,with the hope of providing ideas for the subsequent research.
关键词
肠道干细胞/能量代谢/肠道疾病/中医药/综述
Key words
Intestinal stem cells/Energy metabolism/Intestinal diseases/Traditional Chinese medicine/Review
维普
万方数据