中国全科医学2024,Vol.27Issue(28) :3540-3545.DOI:10.12114/j.issn.1007-9572.2023.0591

社区老年人抑郁和认知状况与营养代谢的关联性研究

Correlation Analysis between Depressive,Cognitive Symptoms and Nutritional Metabolism in the Elderly in Community

郁海东 潘苗苗 顾红琴 刘涛 戴洁 刘玲华 侯俊平 杨丽 施美芳 赵超
中国全科医学2024,Vol.27Issue(28) :3540-3545.DOI:10.12114/j.issn.1007-9572.2023.0591

社区老年人抑郁和认知状况与营养代谢的关联性研究

Correlation Analysis between Depressive,Cognitive Symptoms and Nutritional Metabolism in the Elderly in Community

郁海东 1潘苗苗 2顾红琴 1刘涛 1戴洁 1刘玲华 1侯俊平 1杨丽 1施美芳 1赵超2
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作者信息

  • 1. 201999 上海市宝山区友谊街道社区卫生服务中心
  • 2. 200040 上海市,国家老年疾病临床医学研究中心复旦大学附属华山医院;200032 上海市,复旦大学基础医学院病原生物学系老年基础医学研究所
  • 折叠

摘要

背景 随着我国老龄化人口的增多,老年相关的健康问题日益得到关注.相比于临床症状显著的生理性疾病,老年人的心理健康问题常被忽视,潜在的抑郁状态和慢性病的高发共同导致了老年生活质量的下降.此外,老年人中更为常见的代谢性疾病也极大影响了其脑健康状态,可能导致神经损伤和认知功能下降.目的 研究社区老年人抑郁和认知状况及其是否与营养代谢状况相关.方法 于 2020 年 4-8 月选取上海市宝山区友谊街道社区卫生服务中心参与健康体检的社区老年人共 3 767 例为研究对象,收集研究对象的性别、年龄、BMI和腰臀比等资料,进行简易智力状况量表(MMSE)、简版老年抑郁量表(GDS)、简易营养评估量表(MNA)、日常生活活动能力量表(ADL)、智能精神状态量表(MMSE)的评估,依据GDS得分将研究对象分为正常组(≤3 分)、潜在抑郁组(4~7 分)、抑郁组(≥8 分),并通过临床代谢相关指标进行代谢综合征相关疾病评估和 10 年心血管疾病风险评估,采用Pearson相关分析探讨上述指标的相关性.结果 入组的3 767例老年人中男1 502例,女2 265例;不同组别的年龄、MNA得分、MMSE得分、心血管疾病高危风险人数构成比、10 年心血管疾病风险等级比较,差异有统计学意义(P<0.05);相关性分析结果显示,除MMSE维度中的复述能力维度得分外,GDS得分与MMSE总得分和各维度得分均呈负相关(P<0.05),MNA得分、ADL得分均与MMSE得分呈正相关(P<0.05),血葡萄糖(GLU)和糖化血红蛋白(HbA1c)均与MMSE中即刻回忆能力维度得分呈负相关(P<0.05).结论 老年人的抑郁状况与认知功能下降有关,而更好的营养状况与更好的认知表现有关,关注并改善老年人的代谢健康能够更好地提升其心理状态和精神健康.

Abstract

Background With the increase of the aging population,age-related health problems have garnered increasing attention.Compared to physiologic diseases with significant clinical symptoms,the mental health issues of the elderly are often overlooked.The underlying depressive states and high incidence of chronic diseases collectively contribute to a decline in quality of life in old age.Moreover,metabolic diseases,more prevalent in the elderly,significantly impact brain health,potentially leading to neurological damage and cognitive decline.Objective This study aims to investigate the relationship between depression,cognitive status,and nutritional and metabolic status among elderly individuals in the community.Methods We selected 3 767 elderly individuals who participated in physical examinations at the Youyi Street Community Health Service Center in Baoshan District,Shanghai.The demographic data on sex,age,BMI and waist-to-hip ratio were collected.The evaluations included the Mini-Mental State Examination(MMSE),Geriatric Depression Scale(GDS),Mini Nutritional Assessment(MNA),and Activities of Daily Living Scale(ADL).Metabolic syndrome-related diseases and the 10-year cardiovascular disease risk were assessed using clinical metabolic indicators,and Pearson correlation analysis was used to explore the correlations among these indicators.Results This research showed that significant differences were found in age,MNA,MMSE scores,the proportion of people at high risk of cardiovascular disease and the 10-year cardiovascular disease risk grade among the different groups(P<0.05).Correlation analysis indicated that the GDS score was negatively correlated with the total MMSE score and its sub-item scores,except for the repetition ability score.MNA and ADL were positively correlated with the total MMSE score(P<0.05).Additionally,GLU and HbA1c levels were negatively correlated with immediate recall ability in the MMSE(P<0.05).Conclusion Our findings suggest that depression in the elderly is associated with cognitive decline,while better nutritional status is linked to improved cognitive performance.Focusing on and improving metabolic health in the elderly may enhance their mental state and overall mental health.

关键词

抑郁症/认知功能/营养状况/心血管疾病/老年人/医院,社区/相关性分析

Key words

Depressive disorder/Cognitive function/Nutritional status/Cardiovascular diseases/Aged/Hospitals,community/Correlation analysis

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基金项目

国家重点研发计划(2018YFC2000204)

上海市宝山区科学技术委员会医学卫生项目(2023-E-61)

上海市宝山区科学技术委员会医学卫生项目(21-E-46)

出版年

2024
中国全科医学
中国医院协会

中国全科医学

CSTPCD北大核心
影响因子:2.04
ISSN:1007-9572
参考文献量6
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