保留比值受损肺功能人群胸部CT特征的研究进展
Research Progress on Chest CT Features of the Preserved Ratio Impaired Spirometry Population
黄锦海 1李允 1高怡1
作者信息
- 1. 510010 广东省广州市,广州医科大学附属第一医院国家呼吸系统疾病临床医学研究中心国家呼吸医学中心呼吸疾病全国重点实验室广州呼吸健康研究院
- 折叠
摘要
保留比值受损肺功能(PRISm)是一种常见的肺功能障碍,其被认为是慢性阻塞性肺疾病前期阶段,近年来颇受学术界的关注.尽管目前已有研究者对PRISm群体病因、流行病学、危险因素等方面进行了综述,但是有关胸部CT影像学的检查尚缺乏较为全面的综述.为了更加深入且全面地了解这一人群,本文对PRISm人群胸部CT影像学特征进行总结,评估方法包括视觉评估及定量评估,评估内容包括气道、肺实质及血管的特征变化.本文表明PRISm人群单纯根据胸部CT视觉评估得到的CT影像学特征的参考价值有限,胸部CT的定量评估及其联合肺功能检查指标有利于深入了解PRISm人群的肺部结构特征,并建议在未来开展更多的系统性研究,如前瞻性、大样本、多中心队列研究,以阐述PRISm人群的胸部影像学特征.
Abstract
Preserved ratio impaired spirometry(PRISm)is a common pulmonary functional impairment,considered a pre-chronic obstructive pulmonary disease stage and has received increased attention from the academic community in recent years.Despite a comprehensive review of the etiology,epidemiology,and risk factors of the PRISm population,there is a lack of systematic review for chest CT imaging.To gain a more comprehensive understanding of this population,this article summarizes the chest CT imaging features of the PRISm population using both visual and quantitative assessment methods,including the characteristic changes of airways,lung parenchyma,and vessels.The article indicates that the reference value of visual assessment of chest CT results for the PRISm population is limited,while quantitative assessment of chest CT,combined with pulmonary function testing,is advantageous in gaining a deeper understanding of the lung structural features of the PRISm population.Future studies are expected to employ a more systematic approach through prospective,large-sample,multi-center cohort studies to elucidate the characteristics of the PRISm population in chest imaging.
关键词
保留比值受损肺功能/慢性阻塞性肺疾病/胸部CT/肺功能检查/综述Key words
Preserved ratio impaired spirometry/Chronic obstructive pulmonary disease/Chest CT/Pulmonary function test/Review引用本文复制引用
基金项目
国家重点研发计划项目(2018YFC1311900)
广州国家实验室科研任务项目支持(SRPG22-018)
广东省医学科学技术研究基金(C2021073)
出版年
2024
国家科技期刊平台
NSTL
万方数据