中国全科医学2024,Vol.27Issue(33) :4204-4209.DOI:10.12114/j.issn.1007-9572.2023.0377

雌激素及其受体在病理性疼痛中的作用机制

Mechanism of Estrogen and Estrogen Receptors in Pathologic Pain

何帮靖 周明旺 张朋威
中国全科医学2024,Vol.27Issue(33) :4204-4209.DOI:10.12114/j.issn.1007-9572.2023.0377

雌激素及其受体在病理性疼痛中的作用机制

Mechanism of Estrogen and Estrogen Receptors in Pathologic Pain

何帮靖 1周明旺 2张朋威1
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作者信息

  • 1. 730000 甘肃省兰州市,甘肃中医药大学
  • 2. 730000 甘肃省兰州市,甘肃省中医院矫形骨科
  • 折叠

摘要

病理性疼痛是一种严重的慢性疾病,包括炎症性疼痛、神经病理性疼痛和癌性疼痛.大量研究证实,雌激素及其受体与病理性疼痛之间密切相关,对其发生和发展有着不可忽视的作用.结合近几年国内外相关文献,本文阐述了雌激素及其受体在病理性疼痛中作用机制的相关研究进展,旨在为病理性疼痛的防治和治疗提供理论依据并指导未来研究方向.

Abstract

Pathologic pain is a serious chronic disease,including inflammatory pain,neuropathic pain and cancer pain.Previous studies have proved a close correlation of estrogen and its receptors with pathologic pain,which plays an important role in its occurrence and development,therefore,it has attracted the attention of many researchers at home and abroad.Combining the relevant literature at home and abroad in recent years,this paper reviews the relevant research progress of the mechanism of estrogen and its receptors in pathologic pain,in order to provide a theoretical basis for the prevention and treatment of pathologic pain,as well as the guidance for future research.

关键词

雌激素/雌激素受体/炎症性疼痛/神经病理性疼痛/癌性疼痛

Key words

Estrogens/Estrogen receptor/Inflammatory pain/Neuropathic pain/Cancer pain

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基金项目

国家自然科学基金资助项目(81860861)

国家自然科学基金资助项目(82060876)

中医药高级人才工作室建设项目()

出版年

2024
中国全科医学
中国医院协会

中国全科医学

CSTPCD北大核心
影响因子:2.04
ISSN:1007-9572
参考文献量5
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