摘要
目的 探讨TRUST和TPPA联合检测对梅毒的监控和诊治价值,为临床诊治梅毒提供实验依据.方法 采用TRUST法和TPPA法测定2 083例血清标本(其中910例梅毒患者血清).结果 对910例梅毒患者血清检测,TRUST法栓出773例阳性,敏感性为84.9%,特异性为96.1%.TPPA法检出899例阳性,敏感性为98.7%,差异有统计学意义(P＜0.05);TPPA法具有很高的特异性和灵敏度.结论 TRUST和TPPA联合检测为临床诊治梅毒提供更有价值的实验依据,更有利于梅毒的监控和诊治.
Abstract
Objective To explore the diagnostic value of TRUST and TPPA in diagnosis of human syphilis and provide experimental theory for the clinical purpose. Methods TRUST and TPPA were used to detect 2 083 serum specimens (including 910 syphilis serum specimens). Results There were 773 positives were detected by TRUSTout of 910 syphilis serum specimens with a positive rates of 84.9 % and a specificity of 96.1%; while there 889 specimens were positive detected by TPPA with the sensitivity and specificity of 98.7 % , there were significant differences in the outcomes between TPPA reagent and TRUST reagent. The specificities and the sensitivities of TPPA were 99.6% and 98.7%; higher than that of TRUST (84.9% and 96.1%). Conclusion TPPA in combination with TRUST is valuable for detecting and diagnosing of human syphilis.
NETL
NSTL
维普
万方数据