首页|道阻且长——鼠疫在当今社会的流行与防控

道阻且长——鼠疫在当今社会的流行与防控

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鼠疫是由鼠疫耶尔森菌感染导致的动物源性传染病,也是我国法定报告甲类传染病和国际检疫传染病.在人类历史上曾经发生过3次世界大流行,当前除南极洲和大洋洲外,各大陆均存在鼠疫自然疫源地.马达加斯加和刚果(金)是目前世界上人间鼠疫流行水平最高的地区.在20世纪中期,我国人间鼠疫流行,1950-1954年平均年报告1 400.8例;1955年后,我国人间鼠疫的大规模暴发得到有效控制,1955-1999年平均年报告24.7例.2000年至今,我国人间鼠疫病例仍未销声匿迹,期间累计报告514例.基于One Health理念的鼠疫控制策略是一种更优解,主要体现为"生态学动物监测"+"人间早期诊断处置"的双重手段.有效的动物监测,对鼠疫波及人间可进行准确预测,做到早期预警;而对人间鼠疫病例进行早期诊断早期处置,在一方面可以有效控制人间疫情扩散,另一方面也能有效降低病死率.
A long way to go-the prevalence,prevention,and control of plague in the contemporary era
Plague is an animal-sourced infectious disease of caused by Yersinia pestis,listed asa Class A notifiable infectious disease in China and an international quarantine infectious disease.It has caused three plague world pandemics in human history.Currently,the natural plague foci are distributed in all continents except Antarctica and Oceania.Madagascar and the Democratic Republic of the Congo(DRC)currently have the highest level of human plague epidemic in the world.In the middle of 20th century,human plague was prevalent in China,with an average of 1 400.8 reported cases per year from 1950 to 1954.After 1955,large-scale outbreaks of human plague were effectively controlled,with an average of 24.7 reported cases per year from 1955 to 1999.From 2000 to the present,human cases have not yet disappeared with a cumulative total of 514 cases had been reported.The plague control strategy based on the One Health concept is a more optimal solution,mainly reflected in the"ecological animal surveillance"and"early diagnosis and disposal of human cases"dual approach.Effective animal surveillance can provide accurate prediction and early warning of the risk that may be spread to humans,while early diagnosis and early treatment of human cases can availably control the spread of the epidemic and effectively reduce the case fatality rate simultaneously.

Plaguehuman caseepidemicanimal surveillance

王鑫、景怀琦、阚飙

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中国疾病预防控制中心传染病预防控制所,北京 102206

鼠疫 人间病例 流行 动物监测

国家重点研发计划

2022YFC2602203

2024

中国热带医学
中华预防医学会,海南疾病预防控制中心

中国热带医学

CSTPCD北大核心
影响因子:0.722
ISSN:1009-9727
年,卷(期):2024.24(1)
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