首页|安徽省2017-2021年成人血脂水平变化趋势和地域差异

安徽省2017-2021年成人血脂水平变化趋势和地域差异

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目的 了解35岁及以上成人血清中血脂浓度的变化趋势及血脂异常的流行现状,并比较血脂的地域差异.方法 利用2017-2021年中国心血管病高危人群早期筛查与综合干预项目中安徽省数据,根据年份和省内不同地区绘制血脂水平的变化趋势和各地区患病率,采用多因素回归模型分析血脂异常的影响因素.结果 每年总胆固醇(total cholesterol,TC)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)、非高密度脂蛋白胆固醇(non-high-density lipoprotein cholesterol,non-HDL-C)的整体平均水平都随着年龄增加呈先上升后轻度下降趋势,而高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)、甘油三酯(triglycerides,TG)水平波动较小.2017-2020年TC水平逐年改善,而2021年再次升高.与TG和non-HDL-C相同,2017-2019年LDL-C的平均水平逐年下降,而2020-2021年血脂水平较前3年出现回弹.相反,HDL-C水平仍呈下降趋势.除HDL-C,皖北(n=31 716)整体血脂水平高于皖南(n=50 681),皖中(n=38 246)最低.高胆固醇血症(7.400%,2 347/31 716)、高 LDL-C血症(5.228%,1 658/31 716)、低 HDL-C 血症(9.935%,3 151/31 716)、高TG血症(18.212%,5 776/31 716)、高 non-HDL-C 血症(5.789%,1 836/31 716)患病率均以皖北最高.年龄、地区、高中及以上学历、吸烟、饮酒、收缩压、血糖、体重指数为血脂异常的独立因素(P<0.05).结论 安徽省≥35岁成人的血脂水平及血脂异常患病率状况仍未达到理想控制水平,尤其皖北地区,还需进一步提高对血脂及相关疾病的认识,及时进行干预措施,有效延长居民寿期.
Trends and regional differences in blood lipid levels among adults in Anhui Province from 2017 to 2021
Objective To understand the trends of serum lipid concentration and the prevalence of dyslipidemia in adults aged 35 years and older,and to compare the regional differences in lipids.Methods Based on the data of Anhui Province in the Early Screening and Comprehensive Intervention Project for High-risk Groups of Cardiovascular Disease in China from 2017 to 2021,the change trend of blood lipid level and the prevalence rate of each region were plotted according to the year and different regions in the province,and the influencing factors of dyslipidemia were analyzed by multivariate regression model.Results The overall average levels of total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),and non-high-density lipoprotein cholesterol(non-HDL-C)demonstrated an increase followed by a slight decrease with age annually,while the levels of high-density lipoprotein cholesterol(HDL-C)and triglycerides(TG)fluctuated minimally.From 2017 to 2020,TC levels improved annually but increased again in 2021.Similar to TG and non-HDL-C,the average LDL-C level decreased annually from 2017 to 2019,while rebounded in 2020 and 2021 compared with the previous three years.In contrast,the HDL-C level continued to decline.With the exception of HDL-C,the overall blood lipid levels in the northern Anhui(n=31 716)were higher than those in the southern Anhui(n=50 681),and the lowest levels were found in the central Anhui(n=38 246).The prevalence of hypercholesterolemia(7.400%,2 347/31 716),high LDL-C(5.228%,1 658/31 716),low HDL-C(9.935%,3 151/31 716),hypertriglyceridemia(18.212%,5 776/31 716),and high non-HDL-C(5.789%,1 836/31 716)were highest in the northern Anhui.Age,region,senior high school or above,smoking,drinking,systolic blood pressure,blood glucose,and body mass index were independent factors for dyslipidemia(P<0.05).Conclusion The blood lipid level and prevalence of dyslipidemia in adults aged ≥35 years in Anhui Province have not yet reached an ideal control level,especially in the northern part of Anhui Province where there is a need for enhanced awareness and timely intervention measures for lipid-related diseases to effectively extend the life expectancy of residents.

Lipid trendsdyslipidemiaprevalenceregional differencesAnhui Province

胡益、顾怀聪、张波、王为强

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安徽医科大学附属宿州医院(安徽省宿州市立医院)全科医学科,安徽宿州 234000

血脂趋势 血脂异常 患病率 地域差异 安徽省

安徽省科技创新战略与软科学研究专项计划项目

202106f01050042

2024

中国热带医学
中华预防医学会,海南疾病预防控制中心

中国热带医学

CSTPCD北大核心
影响因子:0.722
ISSN:1009-9727
年,卷(期):2024.24(2)
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