A case of neurobrucellosis in children and literature review
An analysis was conducted on the clinical manifestations,auxiliary examinations,diagnosis and treatment process,treatment,and prognosis of a child with neurobrucellosis.408 relevant literature on neurobrucellosis from January 2012 to December 2022 were searched through Chinese and English databases such as CNKI,Wanfang Data,and Biomedical Literature Database(PubMed).Literature was screened based on inclusion and exclusion criteria,A total of 14 children with neurobrucellosis were selected for analysis,with an average age of onset of 10 years old.Among the patients,there were 3 cases of middle cranial nerve injury,2 cases of ataxia,1 case of myelitis,2 cases of mental symptoms,1 case of optic disc edema,1 case of sagittal sinus thrombosis,and the rest were manifested as meningitis and encephalitis.The imaging results suggested that there was often no specific area of invasion,with magnetic resonance imaging(MRI)commonly involving the cortex,central half oval,and basal ganglia.Extensive white matter changes were also frequently observed,which is consistent with the findings of this case report.Neurobrucellosis has diverse clinical manifestations and lacks specificity.It is mainly diagnosed based on comprehensive analysis of neuropsychiatric symptoms,cerebrospinal fluid and serological results,imaging characteristics,etc.Early diagnosis and treatment are of great significance in preventing complications of neurobrucellosis.
Neurobrucellosischildrenclinical featuresimaging features
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