Successful treatment of a patient with sepsis caused by infection with Vibrio vulnificus following contact with seawater:a case analysis
Vibrio vulnificus infection has a high disability rate and fatality rate.This paper summarized the diagnosis and treatment of a case of Vibrio vulnificus sepsis to help clinicians in the early detection and optimization of treatment options for such infections,thereby providing a clinical reference for related research.In September 2022,a case of sepsis caused by Vibrio vulnificus infection was admitted to the Emergency Department of Hainan Hospital of Traditional Chinese Medicine.Clinical treatment was conducted,and the report was analyzed.Meanwhile,Vibrio vulnificus literature was reviewed to analyze and summarize the treatment methods of Vibrio vulnificus sepsis.The 61-year-old patient was treated in the Emergency Department from September 23 to October 8,2022,during which bacteriological examination of pus and wound infection samples identified the infection as being caused by Vibrio vulnificus.Therefore,targeted treatment with meropenem injection plus levofloxacin injection was administered for the infection,and early CRRT(continuous renal replacement therapy)was implemented to control the inflammatory cytokine storm of sepsis,and surgical debridement treatment was performed.After the patient's condition stabilized,the patient was transferred to the vascular surgery department,where two debridement+left lower limb skin grafting procedures were performed on October 27 and November 19.Then a third debridement+left lower limb third skin grafting+toe amputation was performed on December 10,the patient was discharged with improved condition post-surgery.At present,the patient can live independently and can move the affected limb autonomously.In clinical diagnosis and treatment of sepsis caused by Vibrio vulnificus infection,attention should be paid to the inflammatory cascade reaction.CRRT can eliminate inflammatory factors in the early stage,sensitive antibiotics for anti-inflammatory,surgical debridement interventional treatment,and multi-disciplinary linkage can be initiated to treat patients with Vibrio vulnificus sepsis.
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