山东省2023-2024年猴痘病例流行病学及临床特征
Epidemiological and clinical characteristics of mpox cases in Shandong Province,2023-2024
段青 1李琛 2张玉薇 1逄博 1田雪莹 1张晓梅 1丁淑军 1寇增强1
作者信息
- 1. 山东省疾病预防控制中心,山东 济南 250014;山东省传染病智慧化监测预警和防控重点实验室,山东 济南 250014
- 2. 山东省疾病预防控制机构公共卫生医师规范化培训项目,山东 济南 250014
- 折叠
摘要
目的 了解2023-2024年山东省猴痘病例流行病学特征,为猴痘疫情科学防控提供依据.方法 于中国疾病预防控制信息系统及中国疾病预防控制中心流行病学调查信息系统获取山东省猴痘病例信息及个案调查信息.采用描述性流行病学方法分析猴痘病例流行特征,采用SPSS 25.0统计软件进行统计分析.结果 2023年6月15日青岛市报告山东省首例猴痘确诊病例,截至2024年12月全省累计报告病例61例,无死亡病例.病例均为男性,中位年龄M(P25,P75)为33(29,38)岁.53例(86.9%)、23例(37.7%)、15例(24.6%)和35例(57.4%)分别自述为男男性行为者(men who have sex with men,MSM)、艾滋病病毒感染者、梅毒感染者和在发病前21d有同性性接触史.2023年7月达到发病高峰,随后病例逐渐减少至每月3例以下.病例来源涉及山东省的11个地市,济南市和青岛市共计报告34例(占55.7%),病例均为主动就诊发现,发病至就诊时间间隔M(P25,P75)为3(2,6)d,发病至诊断时间间隔M(P25,P75)为 6(4,9)d.病例主要临床症状为皮疹60例(占98.4%)、发热44例(占72.1%)、皮肤瘙痒31例(占50.8%)和淋巴结肿大26例(占42.6%).结论 山东省猴痘疫情呈散发分布,涉疫人群局限,主要为MSM.建议利用社会组织加强对MSM群体健康教育,加强对医疗机构培训,实现猴痘疫情早发现、早诊断、早治疗,降低疫情传播风险.
Abstract
Objective To describe the epidemiological characteristics of mpox cases reported in Shandong Province from 2023 to 2024 and provide a basis for scientific prevention and control of mpox epidemics.Methods Information on mpox cases and case studies in Shandong Province was obtained from the China Information System for Disease Control and Prevention and the Epidemiological Survey Information System of the Chinese Center for Disease Control and Prevention.Descriptive epidemiological methods were used to analyze the epidemiological characteristics of mpox cases,and SPSS 25.0 statistical software was used for statistical analysis.Results The first confirmed case of mpox in Shandong Province was reported in Qingdao on June 15,2023,and the cumulative number of cases reported up to December 2024 was 61,with no deaths.The cases were all male with age M(P25,P75)of 33(29,38)years.53(86.9%)self-reported MSM,23(37.7%)self-reported HIV infection,15(24.6%)self-reported syphilis infection,and 35(57.4%)self-reported a history of homosexual contact in the 21 days prior to the onset of illness.The incidence of the disease reached a peak in July 2023,and then gradually declined to fewer than 3 cases per month.Eleven cities in Shandong Province were involved,with a total of 34 cases(55.7%)reported in Jinan and Qingdao.The cases were all detected on their own initiative,with an onset-to-visit interval M(P25,P75)of 3(2,6)days and an onset-to-diagnosis interval M(P25,P75)of 6(4,9)days.The main clinical symptoms of the cases were rash in 60 cases(98.4%),fever in 44 cases(72.1%),itchy skin in 31 cases(50.8%)and enlarged lymph nodes in 26 cases(42.6%).Conclusion Mpox in Shandong Province shows sporadic distribution and is largely confined to the MSM population.Strengthening health education for MSM through community organizations and enhancing training for healthcare facilities are recommended to achieve early detection,diagnosis,and treatment,thereby reducing the risk of epidemic transmission.
关键词
猴痘/男男性行为者/合并艾滋病病毒感染/皮疹/发热/皮肤瘙痒Key words
Mpox/men who have sex with men/combined AIDS virus infection/rash/fever/pruritus引用本文复制引用
出版年
2025
NETL
NSTL
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